SCHEMBL6546922

SCHEMBL6546922

CCc1ccc(C(C)=CCc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.50
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
TAS2R14 Q9NYV8 1/20 0.39
MAOB P27338 1/20 0.39
PLK1 P53350 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548028 0.95 TP53 (0.46) TP53ALDH1A1SMN1; SMN2
SCHEMBL29626995 0.87 LMNA (0.56) LMNA
SCHEMBL437687 0.87 MAOB (0.46) LMNAMAOB
SCHEMBL437686 0.87 MAOB (0.46) LMNAMAOB
SCHEMBL437685 0.87 MAOB (0.46) LMNAMAOB
SCHEMBL6547171 0.84 GPR52 (0.44) ALDH1A1SMN1; SMN2MAOB
SCHEMBL6548125 0.80 MEN1 (0.43) ALDH1A1LMNASMN1; SMN2
SCHEMBL9588485 0.79 GPR52 (0.43) ALDH1A1MAOB
SCHEMBL5918848 0.79 TRPA1 (0.56) ALDH1A1LMNASMN1; SMN2MAOB
SCHEMBL5918844 0.79 TRPA1 (0.56) ALDH1A1LMNASMN1; SMN2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed