Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | CPN1 | P15169 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618570 | 0.93 | CTSS (0.46) | CTSKCTSSS1PR3ADRB2ADRB1 | |
| SCHEMBL10093129 | 0.93 | CTSS (0.46) | CTSKCTSSS1PR3ADRB2ADRB1 | |
| SCHEMBL2233904 | 0.89 | CTSK (0.50) | CTSKCTSSS1PR3KLK5GABRB1 | |
| SCHEMBL11065297 | 0.89 | CTSK (0.50) | CTSKCTSSS1PR3KLK5GABRB1 | |
| SCHEMBL9261922 | 0.89 | CTSK (0.50) | CTSKCTSSS1PR3KLK5GABRB1 | |
| SCHEMBL4960665 | 0.83 | CTSK (0.46) | CTSKCTSSADRB2ADRB1ADRB3 | |
| SCHEMBL31226578 | 0.83 | CTSK (0.46) | CTSKCTSSADRB2ADRB1ADRB3 | |
| SCHEMBL22851708 | 0.83 | CTSK (0.46) | CTSKCTSSADRB2ADRB1ADRB3 | |
| SCHEMBL18435386 | 0.83 | CTSK (0.64) | CTSKCTSSS1PR3GABRB1GABRB2 | |
| SCHEMBL16791251 | 0.81 | HPGDS (0.49) | CTSKCTSSS1PR3KLK5GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142317-A1 | Use of amino acid transporter atbo,+ as a delivery system for drugs and prodrugs | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-07-22 | — | — | US | disclosed |
| EP-1384081-A2 | USE OF AMINO ACID TRANSPORTER ATB0,+ AS A DELIVERY SYSTEM FOR DRUGS AND PRODRUGS | Medical College Of Georgia Research Institute, Inc. (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002083060-A2 | USE OF AMINO ACID TRANSPORTER ATB0,+ AS A DELIVERY SYSTEM FOR DRUGS AND PRODRUGS | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2002-10-24 | — | — | WO | disclosed |