Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 15/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616 | 0.92 | TRPV1 (0.55) | KIF11TRPV1ALDH1A1TSHR | |
| Phosphine SCHEMBL28192244 | 0.89 | TRPV1 (0.53) | KIF11TRPV1ALDH1A1TSHR | |
| SCHEMBL25191871 | 0.89 | TRPV1 (0.53) | KIF11TRPV1ALDH1A1TSHR | |
| SCHEMBL26566399 | 0.87 | KIF11 (0.48) | KIF11TRPV1MAOB | |
| SCHEMBL26564601 | 0.87 | KIF11 (0.48) | KIF11TRPV1MAOB | |
| SCHEMBL197238 | 0.86 | KIF11 (0.78) | KIF11MAOBCA1CA2ALDH1A1 | |
| SCHEMBL13410633 | 0.86 | KIF11 (0.78) | KIF11MAOBCA1CA2ALDH1A1 | |
| SCHEMBL29914837 | 0.86 | KIF11 (0.78) | KIF11MAOBCA1CA2ALDH1A1 | |
| SCHEMBL26557911 | 0.85 | KIF11 (0.47) | KIF11TRPV1MAOB | |
| SCHEMBL5695842 | 0.84 | TRPV1 (0.50) | KIF11TRPV1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212139-B2 | Aryl substituted indoles and their use as blockers of sodium channels | PURDUE PHARMA, L.P. (US) | 2015-12-15 | — | — | US | disclosed |
| US-9212139-B2 | Aryl substituted indoles and their use as blockers of sodium channels | PURDUE PHARMA, L.P. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20130296281-A1 | Aryl Substituted Indoles and Their Use as Blockers of Sodium Channels | PURDUE PHARMA L.P. (US) | 2013-11-07 | — | — | US | disclosed |
| US-20130296281-A1 | Aryl Substituted Indoles and Their Use as Blockers of Sodium Channels | PURDUE PHARMA L.P. (US) | 2013-11-07 | — | — | US | disclosed |
| EP-1135977-B1 | METHOD OF MANUFACTURING AN INTERLAYER VIA AND A LAMINATE PRECURSOR USEFUL THEREFOR | HONEYWELL INT INC (US) | 2004-01-28 | — | — | EP | disclosed |
| US-6368697-B1 | Method of manufacturing an interlayer via and a laminate precursor useful for same | HONEYWELL INTERNATIONAL INC. | 2002-04-09 | — | — | US | disclosed |
| EP-0703499-B1 | Top coats for shoot and run printing plates | MINNESOTA MINING & MFG (US) | 2002-03-20 | — | — | EP | disclosed |
| US-6255039-B1 | Fabrication of high density multilayer interconnect printed circuit boards | ISOLA LAMINATE SYSTEMS CORP. | 2001-07-03 | — | — | US | disclosed |
| US-6168898-B1 | A POSITIVE ACTING, PHOTOIMAGEABLE COMPOSITION HAVING, A PHOTOACID GENERATOR CAPABLE OF GENERATING AN ACID UPON EXPOSURE TO ACTINIC RADIATION, A STYRENE-MALEIC ANHYDRIDE COPOLYMER, AN EPXOY, AND A CURING CATALYST | ISOLA LAMINATE SYSTEMS CORP. | 2001-01-02 | — | — | US | disclosed |
| EP-1062545-A1 | POSITIVE ACTING PHOTODIELECTRIC COMPOSITION | Isola Laminate Systems Corporation (US) | 2000-12-27 | — | — | EP | disclosed |
| WO-1996035143-A1 | ACID BLEACHABLE DYE CONTAINING LITHOGRAPHIC PRINTING PLATE COMPOSITION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-11-07 | — | — | WO | disclosed |
| US-5552260-A | PHOTOSENSITIVE COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5395734-A | Acid-sensitive acrylate polymers, iodonium photoinitiator, printing plates | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-03-07 | — | — | US | disclosed |
| EP-0600615-A2 | Shoot and run printing materials | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-06-08 | — | — | EP | disclosed |
| EP-0599463-A2 | High speed, dry processed printing plate construction | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5314785-A | Photoinitiator which generates acid on exposure, polymer containing acid labile alkoxy alkyl ester pendant groups | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0559660-A1 | PHOTOSENSITIVE MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5225316-A | A photoinitiator that generates acid on exposure to radiation and a polymer with an acid labile group | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| WO-1992009934-A1 | PHOTOSENSITIVE MATERIALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-06-11 | — | — | WO | disclosed |
| US-5102771-A | Containing photoinitiator and polymer containing alkoxyalkyl ester groups | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296281-A1 | Aryl Substituted Indoles and Their Use as Blockers of Sodium Channels | SCN5A, TRPV1, TRPV5 | KIF11 3095/4885TRPV1 2/4885MAOB 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.