SCHEMBL6548152

SCHEMBL6548152

C=C(c1ccc(C)cc1C)c1ccccc1CC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.43
NFE2L2 Q16236 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
KMT2A Q03164 3/20 0.41
HTT P42858 1/20 0.41
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
TAS1R2 Q8TE23 1/20 0.40
MEN1 O00255 2/20 0.40
KDM4E B2RXH2 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
IDO1 P14902 1/20 0.39
TDO2 P48775 1/20 0.39
MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546961 0.84 HPGD (0.47) SMN1; SMN2KMT2AHTTMEN1KDM4E
SCHEMBL6547421 0.84 MAPK14 (0.44) HSD11B1NFE2L2SMN1; SMN2KMT2AHTT
SCHEMBL11616146 0.83 HSD11B1 (0.47) HSD11B1NFE2L2SMN1; SMN2KMT2AHTT
SCHEMBL6546236 0.82 GABRA1 (0.48) HTTTSHRMAPT
SCHEMBL6547363 0.82 TDP1 (0.48) HSD11B1NFE2L2SMN1; SMN2KMT2AHTT
SCHEMBL29883022 0.82 TDP1 (0.48) HSD11B1NFE2L2SMN1; SMN2KMT2AHTT
SCHEMBL22078945 0.79 KMT2A (0.43) HSD11B1NFE2L2SMN1; SMN2KMT2AHTT
SCHEMBL6548146 0.76 GABRA1 (0.41) KMT2AHTTNPC1RAB9AMEN1
SCHEMBL9715732 0.75 NFE2L2 (0.41) HSD11B1NFE2L2SMN1; SMN2KMT2AHTT
SCHEMBL6546292 0.75 NFE2L2 (0.46) HSD11B1NFE2L2SMN1; SMN2KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed