SCHEMBL6548146

SCHEMBL6548146

C=C(c1ccccc1CC)c1cccc(C)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.41
GABRB2 P47870 2/20 0.41
HPGD P15428 2/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
PTGS2 P35354 2/20 0.39
LMNA P02545 2/20 0.39
CYP3A4 P08684 2/20 0.39
AKR1B10 O60218 1/20 0.39
TRPA1 O75762 1/20 0.39
ABCB11 O95342 1/20 0.39
DHFR P00374 1/20 0.39
MPO P05164 1/20 0.39
CYP1A2 P05177 1/20 0.39
CHRM1 P11229 1/20 0.39
CYP2C9 P11712 1/20 0.39
AKR1B1 P15121 1/20 0.39
PTGS1 P23219 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546548 0.88 HPGD (0.42) GABRA1GABRB2HPGDMEN1KMT2A
SCHEMBL6546961 0.87 HPGD (0.47) GABRA1GABRB2HPGDMEN1KMT2A
SCHEMBL10602542 0.86 ESR1 (0.37) HPGDMEN1KMT2APTGS2LMNA
SCHEMBL6546236 0.84 GABRA1 (0.48) GABRA1GABRB2HPGDLMNATP53
SCHEMBL6547365 0.84 TRPA1 (0.48) HPGDMEN1KMT2APTGS2LMNA
SCHEMBL10601734 0.83 MAPK14 (0.43) HPGDMEN1KMT2APTGS2LMNA
SCHEMBL6546966 0.77 CLCN2 (0.41) GABRA1GABRB2HPGDMEN1KMT2A
SCHEMBL6548152 0.76 HSD11B1 (0.43) MEN1KMT2ACYP3A4MAPTHTT
SCHEMBL6546288 0.76 KMT2A (0.42) HPGDMEN1KMT2APTGS2LMNA
SCHEMBL10599801 0.76 ALDH1A1 (0.42) GABRA1GABRB2LMNATP53CLCN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0158809-B1 ELECTRICAL INSULATING OIL AND OIL-FILLED ELECTRICAL APPLIANCES NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-01-25 EP disclosed
US-4618914-A 1,1-DIARYLALKENES; HEAT RESISTANCE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-10-21 US disclosed
EP-0158809-A1 Electrical insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-10-23 EP disclosed