SCHEMBL6548378

SCHEMBL6548378

CC(C)(C)c1ccc(CO/N=C/c2ccc(CCOc3c(Cl)cc(OCC=C(Cl)Cl)cc3Cl)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
RECQL P46063 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
MAPT P10636 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
SPHK2 Q9NRA0 2/20 0.35
SPHK1 Q9NYA1 2/20 0.35
NR1I3 Q14994 2/20 0.34
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548381 1.00 LMNA (0.39) LMNARECQLMEN1KMT2AMAPT
SCHEMBL6549999 0.89 MEN1 (0.41) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL6550005 0.89 MEN1 (0.41) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL6547759 0.86 L3MBTL1 (0.36) LMNAMEN1KMT2AMAPTL3MBTL1
SCHEMBL6547756 0.86 L3MBTL1 (0.36) LMNAMEN1KMT2AMAPTL3MBTL1
SCHEMBL6548336 0.86 MEN1 (0.34) LMNAMEN1KMT2AMAPTL3MBTL1
SCHEMBL6548340 0.86 MEN1 (0.34) LMNAMEN1KMT2AMAPTL3MBTL1
SCHEMBL6549065 0.85 PPARA (0.34) HTTPPARGPPARA
SCHEMBL6549069 0.85 PPARA (0.34) HTTPPARGPPARA
SCHEMBL6548192 0.83 SRC (0.34) MEN1KMT2AMAPTL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 LMNA 3205/4885RECQL 1509/4885MEN1 4425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.