Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2958439 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL6548458 | 0.82 | TRPA1 (0.50) | DAOTRPA1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7111737 | 0.81 | PNP (0.49) | DAOTRPA1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7120147 | 0.80 | DAO (0.40) | DAOTRPA1SMN1; SMN2ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL6258586 | 0.80 | PNP (0.48) | DAOTRPA1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7985648 | 0.79 | HPGD (0.47) | DAOTRPA1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL20187449 | 0.79 | QPCTL (0.47) | TRPA1ALDH1A1KMT2AHPGDGAA | |
| SCHEMBL22533556 | 0.76 | KMT2A (0.41) | TRPA1SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL27441619 | 0.76 | KMT2A (0.41) | TRPA1SMN1; SMN2ALDH1A1KMT2AHPGD | |
| Bromide SCHEMBL6556197 | 0.74 | SIRT2 (0.41) | DAOTRPA1CYP19A1PDE10AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383766-A1 | DISUBSTITUTED 1,7-GUANINES | Pharmacia Italia S.p.A. (IT) | 2004-01-28 | — | — | EP | claimed |
| WO-2002090357-A1 | DISUBSTITUTED 1,7-GUANINES | PHARMACIA ITALIA S.P.A. (IT) | 2002-11-14 | — | — | WO | claimed |
| EP-1383766-A1 | DISUBSTITUTED 1,7-GUANINES | Pharmacia Italia S.p.A. (IT) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090357-A1 | DISUBSTITUTED 1,7-GUANINES | PHARMACIA ITALIA S.P.A. (IT) | 2002-11-14 | — | — | WO | disclosed |