Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812404 | 0.84 | PARN (0.54) | PARNCNOT7GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7977499 | 0.82 | CYP11B1 (0.48) | PARNCNOT7NR1I2ALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL6556197 | 0.81 | SIRT2 (0.41) | DAOCYP19A1PDE10AGAAADORA2A | |
| SCHEMBL6548460 | 0.80 | DAO (0.43) | DAOCYP19A1PDE10AGAAADORA2A | |
| SCHEMBL7985654 | 0.79 | CNOT7 (0.42) | DAOPARNCNOT7CYP19A1PDE10A | |
| SCHEMBL6548458 | 0.75 | TRPA1 (0.50) | DAOCYP19A1PDE10AGAAADORA2A | |
| SCHEMBL7111074 | 0.71 | PNP (0.44) | CYP19A1PDE10AADORA2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7111737 | 0.71 | PNP (0.49) | DAOCYP19A1ADORA2AALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6258586 | 0.70 | PNP (0.48) | DAOCYP19A1ADORA2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7118850 | 0.70 | BACE1 (0.49) | CNOT7PDE10AADORA2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030186978-A1 | Novel telomerase inhibitors | PHARMACIA ITALIA, SPA (IT) | 2003-10-02 | — | — | US | claimed |
| WO-2001096339-A1 | NOVEL TELOMERASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186978-A1 | Novel telomerase inhibitors | TERT, TERF2IP, TERF2 | DAO 4100/4885PARN 3206/4885CNOT7 1833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.