SCHEMBL6548604

SCHEMBL6548604

O=C1NC(=O)C2(CCCCC2)NC12CCCCC2

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 14/20 0.35
POLB P06746 2/20 0.34
KMT2A Q03164 1/20 0.32
PDE7B Q9NP56 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548145 0.77 POLB (0.30) POLB
SCHEMBL6549507 0.75 PDE7A (0.37) PDE7APOLBKMT2APDE7B
SCHEMBL11583573 0.74
SCHEMBL351324 0.74 PDE7A (0.50) PDE7APDE7B
SCHEMBL22422289 0.74 PDE7A (0.50) PDE7APDE7B
SCHEMBL11870539 0.74 PDE7A (0.50) PDE7APDE7B
SCHEMBL551553 0.74 PDE7A (0.50) PDE7APDE7B
SCHEMBL11491220 0.74 PDE7A (0.50) PDE7APDE7B
SCHEMBL677181 0.71 PGR (0.36) POLB
SCHEMBL23651597 0.70 ALDH1A1 (0.50) PDE7APOLBKMT2APDE7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100143805-A1 NITROXIDES FOR LITHIUM-ION BATTERIES CIBA CORPORATION (NY) 2010-06-10 US disclosed
US-20100143805-A1 NITROXIDES FOR LITHIUM-ION BATTERIES CIBA CORPORATION (NY) 2010-06-10 US disclosed
WO-2008110466-A1 NITROXIDES FOR LITHIUM-ION BATTERIES BASF SE (CH) 2008-09-18 WO disclosed
EP-1383832-A1 STABILIZED CANDLE WAX Ciba SC Holding AG (CH) 2004-01-28 EP disclosed
WO-2002079313-A1 STABILIZED CANDLE WAX CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed
US-4208522-A POLYMER STABILIZERS CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed
US-4125517-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1978-11-14 US disclosed
US-4070335-A 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1978-01-24 US disclosed
US-4067848-A Alkyl alkanoate derivatives of substituted piperazine-diones and polymer compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1978-01-10 US disclosed
US-4051137-A Substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1977-09-27 US disclosed
US-4007157-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1977-02-08 US disclosed
US-4007156-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1977-02-08 US disclosed
US-3992351-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1976-11-16 US disclosed
US-3969316-A 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-13 US disclosed
US-3968078-A Alkyl alkanoate derivatives of substituted piperazine-diones and polymer compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-06 US disclosed
US-3936456-A Substituted piperazine dione oxyls and hydroxides and polymer compositions stabilized thereby CIBY-GEIGY CORPORATION (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100143805-A1 NITROXIDES FOR LITHIUM-ION BATTERIES OGG1, NOX4, NQO1 PDE7A 3295/4885POLB 1097/4885KMT2A 1319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.