Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | CA1 | P00915 | 6/20 | 0.63 |
| ▸ | CA2 | P00918 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.59 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18723228 | 0.86 | POLB (0.75) | POLBTDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL15507918 | 0.78 | MAPT (1.00) | POLBTDP1L3MBTL1CA1CA2 | |
| SCHEMBL11176849 | 0.78 | POLB (0.63) | POLBTDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL11598628 | 0.76 | POLB (0.65) | POLBTDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL31670541 | 0.75 | CA1 (0.63) | POLBTDP1L3MBTL1CA1CA2 | |
| SCHEMBL329732 | 0.75 | CA1 (0.63) | POLBTDP1L3MBTL1CA1CA2 | |
| SCHEMBL6550219 | 0.75 | POLB (0.60) | POLBTDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL11347777 | 0.75 | POLB (0.60) | POLBTDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL6550216 | 0.74 | POLB (0.62) | POLBTDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL11531125 | 0.74 | LMNA (0.64) | POLBTDP1L3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341754-B1 | SUBSTITUTED ANTHRANILIC ACIDS | AVENTIS PHARMA GMBH (DE) | 2004-12-08 | — | — | EP | disclosed |
| EP-1341754-A1 | SUBSTITUTED ANTHRANILIC ACIDS | Aventis Pharma Deutschland GmbH (DE) | 2003-09-10 | — | — | EP | disclosed |
| US-6593352-B2 | 2-phenylalkylaminobenzoic acid containing substituted benzylsufamoyl group; useful for treating cardiovascular disorders, and for preserving or storing a transplant for surgery | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-07-15 | — | — | US | disclosed |
| US-20020123632-A1 | Substituted anthranilic acids, their use as a medicament or diagnostic, and medicament comprising them, and a pharmaceutical combination preparation containing a sodium/hydrogen exchange (NHE) blocker | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2002-09-05 | — | — | US | disclosed |
| WO-2002046148-A1 | SUBSTITUTED ANTHRANILIC ACIDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123632-A1 | Substituted anthranilic acids, their use as a medicament or diagnostic, and medicament comprising them, and a pharmaceutical combination preparation containing a sodium/hydrogen exchange (NHE) blocker | SLC10A1, SLC9A1, SLC9A2 | POLB 2938/4885TDP1 4130/4885L3MBTL1 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.