Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6551205 | 1.00 | HSP90AA1 (0.40) | HSP90AA1LMNAMAPTESR1SMN1; SMN2 | |
| SCHEMBL9002444 | 0.80 | HTR1A (0.56) | HSP90AA1LMNAMAPTSMN1; SMN2TSHR | |
| SCHEMBL9002435 | 0.80 | HTR1A (0.56) | HSP90AA1LMNAMAPTSMN1; SMN2TSHR | |
| SCHEMBL25373051 | 0.74 | LMNA (0.47) | HSP90AA1LMNAMAPTESR1SMN1; SMN2 | |
| SCHEMBL9097523 | 0.74 | LMNA (0.63) | LMNASMN1; SMN2TYMS | |
| SCHEMBL9097516 | 0.74 | LMNA (0.63) | LMNASMN1; SMN2TYMS | |
| SCHEMBL5664254 | 0.74 | TK1 (0.46) | LMNABCHEALDH1A1 | |
| SCHEMBL8088523 | 0.73 | LMNA (0.45) | HSP90AA1LMNAMAPTESR1SMN1; SMN2 | |
| SCHEMBL26125321 | 0.73 | LMNA (0.43) | HSP90AA1LMNAMAPTSMN1; SMN2TSHR | |
| SCHEMBL9100241 | 0.72 | HSP90AA1 (0.54) | HSP90AA1LMNASMN1; SMN2TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788507-B1 | L-PYRANOSYL NUCLEOSIDES | GENENCOR INT (US) | 2004-12-15 | — | — | EP | disclosed |
| US-5885972-A | ANTICARCINOGENIC AGENT | GENENCOR INTERNATIONAL, INC. (US) | 1999-03-23 | — | — | US | disclosed |