Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.46 |
| ▸ | TYMP | P19971 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13376983 | 0.81 | TK2 (0.44) | TK1TYMPALDH1A1LMNAALB | |
| SCHEMBL7699861 | 0.77 | TK1 (0.45) | TK1TYMPRNASE1BCHE | |
| SCHEMBL6551210 | 0.74 | HSP90AA1 (0.40) | BCHEALDH1A1LMNA | |
| SCHEMBL6551205 | 0.74 | HSP90AA1 (0.40) | BCHEALDH1A1LMNA | |
| SCHEMBL6323252 | 0.73 | RNASE1 (0.59) | TK1RNASE1 | |
| SCHEMBL31355237 | 0.73 | RNASE1 (0.72) | TK1RNASE1 | |
| SCHEMBL8374922 | 0.73 | RNASE1 (0.59) | TK1RNASE1 | |
| SCHEMBL9324697 | 0.73 | RNASE1 (0.58) | TK1RNASE1 | |
| SCHEMBL23784803 | 0.72 | TK1 (0.44) | TK1TYMPHPGDRNASE1ALDH1A1 | |
| SCHEMBL1408672 | 0.72 | TK1 (0.44) | TK1TYMPHPGDRNASE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084125-B2 | Xylo-LNA analogues | EXIQON A/S (DK) | 2006-08-01 | — | — | US | disclosed |