Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 3/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4220258 | 0.83 | PKM (0.60) | KDM4EHSD17B10ALDH1A1TDP1MAPK1 | |
| SCHEMBL5637369 | 0.81 | KDM4E (0.47) | KDM4ECYP3A4HSD17B10HTR6ADRB1 | |
| SCHEMBL10697085 | 0.80 | PDE10A (0.47) | KDM4ECYP3A4HSD17B10ALDH1A1TDP1 | |
| SCHEMBL9700449 | 0.80 | HRH4 (0.56) | KDM4ECYP3A4ALDH1A1USP2CYP1A2 | |
| SCHEMBL10583557 | 0.80 | KDM4E (0.49) | KDM4ECYP3A4HSD17B10HTR6ADRB1 | |
| SCHEMBL10433505 | 0.80 | HTR2C (0.44) | KDM4EHTR3AHTR2CHTR3EHTR3B | |
| SCHEMBL16087144 | 0.80 | KDM4E (0.54) | KDM4ECYP3A4HSD17B10HTR6ADRB1 | |
| SCHEMBL6770354 | 0.78 | ADRB1 (0.56) | KDM4ECYP3A4HSD17B10HTR6ADRB1 | |
| SCHEMBL7261980 | 0.77 | KDM4E (0.76) | KDM4ECYP3A4HSD17B10HTR6ADRB1 | |
| SCHEMBL26617769 | 0.77 | ALDH1A1 (0.46) | KDM4EHSD17B10ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106452100-A | Three-level photovoltaic grid-connected inverter based on DSP control and working method of three-level photovoltaic grid-connected inverter | 江苏建筑职业技术学院 | 2017-02-22 | — | — | CN | claimed |
| EP-0154622-A4 | ANTIMICROBIAL COMPOSITIONS CONTAINING 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(1-PIPERAZINYL)-3-QUINOLINE CARBOXYLIC ACID OR METAL SALTS THEREOF AND SILVER SULFADIAZINE. | RESEARCH CORP (US) | 1987-03-16 | — | — | EP | claimed |
| CN-85101810-A | 7-amido-1-cyclopropyl-6,8-dihalo-1,4-dihydro-4-oxo-3-quinoline carboxylic acid's preparation method | — | 1987-01-17 | — | — | CN | claimed |
| EP-0154622-A1 | ANTIMICROBIAL COMPOSITIONS CONTAINING 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(1-PIPERAZINYL)-3-QUINOLINE CARBOXYLIC ACID OR METAL SALTS THEREOF AND SILVER SULFADIAZINE | Research Corporation (US) | 1985-09-18 | — | — | EP | claimed |
| WO-1985001208-A1 | ANTIMICROBIAL COMPOSITIONS CONTAINING 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(1-PIPERAZINYL)-3-QUINOLINE CARBOXYLIC ACID OR METAL SALTS THEREOF AND SILVER SULFADIAZINE | RESEARCH CORPORATION (US) | 1985-03-28 | — | — | WO | claimed |
| CN-111808011-B | High penetration composition and its application | 泰飞尔生物医药(苏州)有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-105566213-B | The prodrugs composition of antimicrobial and antimicrobial related compound with high-penetration | 上海泰飞尔生化技术有限公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-108697827-A | Antimicrobial solutions with enhancing stability | 得克萨斯州大学系统董事会 | 2018-10-23 | — | — | CN | disclosed |
| CN-108191846-A | High-penetration composition and its application | 于崇曦 | 2018-06-22 | — | — | CN | disclosed |
| CN-107320732-A | High-penetration composition and its application | 于崇曦 | 2017-11-07 | — | — | CN | disclosed |
| CN-107261149-A | High-penetration composition and its application | 于崇曦 | 2017-10-20 | — | — | CN | disclosed |
| CN-106452100-A | Three-level photovoltaic grid-connected inverter based on DSP control and working method of three-level photovoltaic grid-connected inverter | 江苏建筑职业技术学院 | 2017-02-22 | — | — | CN | disclosed |
| EP-0300155-A2 | Cyclopropyl amines | BAYER AG (DE) | 1989-01-25 | — | — | EP | disclosed |
| EP-0276700-A1 | 8-Cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids, process for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1988-08-03 | — | — | EP | disclosed |
| CN-87100799-A | ANTIBACTERIAL DRUGS FOR FISH | — | 1987-09-16 | — | — | CN | disclosed |
| EP-0154622-A4 | ANTIMICROBIAL COMPOSITIONS CONTAINING 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(1-PIPERAZINYL)-3-QUINOLINE CARBOXYLIC ACID OR METAL SALTS THEREOF AND SILVER SULFADIAZINE. | RESEARCH CORP (US) | 1987-03-16 | — | — | EP | disclosed |
| EP-0154622-A1 | ANTIMICROBIAL COMPOSITIONS CONTAINING 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(1-PIPERAZINYL)-3-QUINOLINE CARBOXYLIC ACID OR METAL SALTS THEREOF AND SILVER SULFADIAZINE | Research Corporation (US) | 1985-09-18 | — | — | EP | disclosed |
| US-4528287-A | 6-Fluoro-1, 4-dihydro-4-oxo-7-substituted piperazinylquinoline-3-carboxylic acids and the method for preparing the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1985-07-09 | — | — | US | disclosed |
| EP-0140116-A1 | A 6-fluoro-1,4-dihydro-4-oxo-7-substituted piperazinyl-quinoline-3-carboxylic acid derivative and the method for preparing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1985-05-08 | — | — | EP | disclosed |
| WO-1985001208-A1 | ANTIMICROBIAL COMPOSITIONS CONTAINING 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(1-PIPERAZINYL)-3-QUINOLINE CARBOXYLIC ACID OR METAL SALTS THEREOF AND SILVER SULFADIAZINE | RESEARCH CORPORATION (US) | 1985-03-28 | — | — | WO | disclosed |