Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.55 |
| ▸ | SRC | P12931 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15228351 | 0.90 | NOX4 (0.69) | POLHKDM4EMEN1MMP1POLB | |
| SCHEMBL3982524 | 0.90 | PPARG (0.67) | POLHKDM4EMEN1POLBMAPT | |
| SCHEMBL8055794 | 0.87 | POLH (0.53) | POLHKDM4EMEN1MMP1POLB | |
| SCHEMBL7940149 | 0.85 | PPARG (0.62) | MAPTPPARGABCB1ELANEADORA3 | |
| SCHEMBL15228364 | 0.83 | POLH (0.54) | POLHKDM4EMEN1MMP1POLB | |
| SCHEMBL28516722 | 0.83 | PPARG (0.53) | POLHKDM4EMEN1POLBMAPT | |
| SCHEMBL12691527 | 0.82 | POLH (0.67) | POLHKDM4EMEN1MMP1POLB | |
| SCHEMBL118391 | 0.82 | ADORA3 (0.61) | POLHPOLBMAPTPPARGNOX4 | |
| SCHEMBL29410971 | 0.82 | ADORA3 (0.61) | POLHPOLBMAPTPPARGNOX4 | |
| SCHEMBL30424171 | 0.82 | PPARG (0.69) | MAPTPPARGBCHEABCB1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463514-A2 | UTILIZATION OF RUTINS AND AESCINS IN THE TREATMENT OF OCULAR CIRCULATORY DISTURBANCES | Brench AG (DE) | 2004-10-06 | — | — | EP | disclosed |
| EP-1385578-A1 | UTILIZATION OF RUTINS AND AESCINS IN THE TREATMENT OF CIRCULATORY DISTURBANCES OF THE EAR | Brench AG (DE) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002092063-A2 | UTILIZATION OF RUTINS AND AESCINS IN THE TREATMENT OF OCULAR CIRCULATORY DISTURBANCES | BRENCH AG (DE) | 2002-11-21 | — | — | WO | disclosed |
| WO-2002089918-A1 | UTILIZATION OF RUTINS AND AESCINS IN THE TREATMENT OF CIRCULATORY DISTURBANCES OF THE EAR | BRENCH AG (DE) | 2002-11-14 | — | — | WO | disclosed |