Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552154 | 0.83 | ALDH1A1 (0.35) | MAPTALDH1A1SMN1; SMN2SOAT1 | |
| SCHEMBL8046651 | 0.68 | ALDH1A1 (0.43) | TSHRMAPTALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL7756478 | 0.64 | ALDH1A1 (0.37) | ALOX5TSHRMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5809049 | 0.63 | ALDH1A1 (0.47) | TSHRMAPTALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL7760150 | 0.62 | ALDH1A1 (0.35) | ALOX5TSHRALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL1275935 | 0.62 | ALDH1A1 (0.46) | TSHRMAPTALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL10438826 | 0.61 | ALDH1A1 (0.40) | ALOX5MAPTALDH1A1CYP1A2NPC1 | |
| SCHEMBL4356883 | 0.61 | ALDH1A1 (0.49) | TSHRALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL9137641 | 0.61 | ALDH1A1 (0.65) | TSHRMAPTALDH1A1CYP1A2NPC1 | |
| SCHEMBL7268595 | 0.60 | ALDH1A1 (0.41) | MAPTALDH1A1CYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051402-B1 | METHOD FOR PRODUCING S-ALKYL(ARYL)-SUBSTITUTED IMIDAZOLE DERIVATIVES | AVENTIS PHARMA GMBH (DE) | 2004-12-08 | — | — | EP | disclosed |
| EP-1051402-A1 | METHOD FOR PRODUCING S-ALKYL(ARYL)-SUBSTITUTED IMIDAZOL DERIVATIVES | Aventis Pharma Deutschland GmbH (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037620-A1 | METHOD FOR PRODUCING S-ALKYL(ARYL)-SUBSTITUTED IMIDAZOL DERIVATIVES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-29 | — | — | WO | disclosed |