Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6551633 | 0.83 | ALOX5 (0.35) | ALDH1A1MAPTSOAT1SMN1; SMN2 | |
| SCHEMBL10438826 | 0.65 | ALDH1A1 (0.40) | ALDH1A1MAPTSOAT1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL8709929 | 0.63 | ALDH1A1 (0.33) | ALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL9236366 | 0.62 | ALDH1A1 (0.41) | ALDH1A1MAPTSOAT1POLBSMN1; SMN2 | |
| SCHEMBL7211988 | 0.62 | ALDH1A1 (0.54) | ALDH1A1MAPTSOAT1POLBSMN1; SMN2 | |
| SCHEMBL7756478 | 0.61 | ALDH1A1 (0.37) | ALDH1A1MAPTSOAT1SMN1; SMN2KDM4E | |
| SCHEMBL9080422 | 0.61 | KDM4E (0.44) | ALDH1A1SOAT1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL5243244 | 0.61 | KDM4E (0.44) | ALDH1A1SOAT1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL10004063 | 0.61 | ALDH1A1 (0.48) | ALDH1A1RXFP1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL7013807 | 0.60 | ALDH1A1 (0.48) | ALDH1A1MAPTSOAT1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051402-B1 | METHOD FOR PRODUCING S-ALKYL(ARYL)-SUBSTITUTED IMIDAZOLE DERIVATIVES | AVENTIS PHARMA GMBH (DE) | 2004-12-08 | — | — | EP | disclosed |
| EP-1051402-A1 | METHOD FOR PRODUCING S-ALKYL(ARYL)-SUBSTITUTED IMIDAZOL DERIVATIVES | Aventis Pharma Deutschland GmbH (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037620-A1 | METHOD FOR PRODUCING S-ALKYL(ARYL)-SUBSTITUTED IMIDAZOL DERIVATIVES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-29 | — | — | WO | disclosed |