SCHEMBL6551909

SCHEMBL6551909

C=C(CCCCCO)c1ccc(C(=O)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
TP53 P04637 2/20 0.44
GPR84 Q9NQS5 1/20 0.43
FFAR1 O14842 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43
HDAC1 Q13547 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
SRD5A2 P31213 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA12 O43570 1/20 0.39
CA3 P07451 1/20 0.39
TYR P14679 1/20 0.39
DRD1 P21728 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14404131 0.87 MAPK1 (0.49) TSHRTP53GPR84FFAR1FFAR4
Terephthalic Acid SCHEMBL11878692 0.84 TSHR (0.63) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL6389843 0.84 TSHR (0.63) TSHRTP53SRD5A2CA1CA2
SCHEMBL8408078 0.84 TP53 (0.56) TSHRTP53ALDH1A1MAPT
SCHEMBL13316192 0.82 L3MBTL1 (0.47) GPR84FFAR1FFAR4HDAC1HDAC8
Terephthalic Acid SCHEMBL27915155 0.82 GPR84 (0.67) TSHRTP53GPR84FFAR1FFAR4
Sebacic Acid SCHEMBL28904447 0.82 GPR84 (0.67) TSHRTP53GPR84FFAR1FFAR4
Sebacic Acid SCHEMBL28058541 0.82 GPR84 (0.67) TSHRTP53GPR84FFAR1FFAR4
Sebacic Acid SCHEMBL78409 0.82 GPR84 (0.67) TSHRTP53GPR84FFAR1FFAR4
Terephthalic Acid SCHEMBL2778330 0.82 TSHR (0.60) TSHRTP53SRD5A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 EP disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed