Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL29140889 | 0.88 | HDAC3 (0.55) | MAPK1HDAC1HDAC8HDAC3HDAC4 | |
| Sebacic Acid SCHEMBL30734379 | 0.88 | LMNA (0.60) | MAPK1HDAC1HDAC8HDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL11145819 | 0.88 | LMNA (0.60) | MAPK1HDAC1HDAC8HDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL28178132 | 0.88 | LMNA (0.60) | MAPK1HDAC1HDAC8HDAC3HDAC4 | |
| Octanedioate SCHEMBL29154819 | 0.88 | LMNA (0.60) | MAPK1HDAC1HDAC8HDAC3HDAC4 | |
| Azelaic Acid SCHEMBL351913 | 0.88 | LMNA (0.60) | MAPK1HDAC1HDAC8HDAC3HDAC4 | |
| Sebacic Acid SCHEMBL352890 | 0.88 | LMNA (0.60) | MAPK1HDAC1HDAC8HDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL9850543 | 0.88 | LMNA (0.60) | MAPK1HDAC1HDAC8HDAC3HDAC4 | |
| Terephthalic Acid SCHEMBL28198648 | 0.88 | LMNA (0.60) | MAPK1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL6551909 | 0.87 | TSHR (0.44) | HDAC1HDAC8TSHRLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120459-A2 | CHIRAL DIOLE COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS AND POLYMER NETWORKS DERIVED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |