SCHEMBL6552137

SCHEMBL6552137

[c]1c2c(cc(-c3cccc4ccccc34)c1-c1cccc3ccccc13)-c1ccccc1C2

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.35
HTR1A P08908 2/20 0.35
KDM4E B2RXH2 3/20 0.33
NPC1 O15118 2/20 0.33
MAPT P10636 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CYP2D6 P10635 2/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
PKM P14618 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALPL P05186 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2961803 0.78 KDM4E (0.32) KDM4ENPC1MAPTRAB9ASMN1; SMN2
Fluorene SCHEMBL28714196 0.77 MAOA (0.48) HTR7HTR1AKDM4ENPC1MAPT
SCHEMBL2966371 0.76 KDM4E (0.34) HTR7HTR1AKDM4ENPC1MAPT
SCHEMBL1029595 0.76 KDM4E (0.34) HTR7HTR1AKDM4ENPC1MAPT
SCHEMBL2966010 0.74 KDM4E (0.34) KDM4ENPC1MAPTRAB9ASMN1; SMN2
SCHEMBL2975649 0.72 TRPA1 (0.34) KDM4ENPC1MAPTRAB9ASMN1; SMN2
SCHEMBL6675750 0.72 PNMT (0.50) HTR7HTR1AKDM4ENPC1MAPT
SCHEMBL29555007 0.72 PNMT (0.50) HTR7HTR1AKDM4ENPC1MAPT
SCHEMBL1539776 0.72 ALDH1A1 (0.36) KDM4ENPC1MAPTRAB9ASMN1; SMN2
SCHEMBL2973470 0.71 KDM4E (0.31) KDM4ENPC1MAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993478-A1 OLEFIN POLYMERIZATION PROCESS BOREALIS A/S (DK) 2000-04-19 EP claimed
WO-1998058001-A1 OLEFIN POLYMERIZATION PROCESS COCKBAIN, JULIAN (GB) 1998-12-23 WO claimed
EP-1385890-A2 OLEFIN POLYMERISATION PROCESS Borealis Technology Oy (FI) 2004-02-04 EP disclosed
WO-2002090398-A2 OLEFIN POLYMERISATION PROCESS BOREALIS TECHNOLOGY OY (FI) 2002-11-14 WO disclosed
EP-1203035-A1 IMPROVEMENTS IN OR RELATING TO POLYMERS Borealis Technology Oy (FI) 2002-05-08 EP disclosed
EP-1093475-A1 CATALYST FOR THE POLYMERISATION OF OLEFINS Borealis Technology Oy (FI) 2001-04-25 EP disclosed
WO-2001009200-A1 IMPROVEMENTS IN OR RELATING TO POLYMERS BOREALIS TECHNOLOGY OY (FI) 2001-02-08 WO disclosed
EP-0993478-A1 OLEFIN POLYMERIZATION PROCESS BOREALIS A/S (DK) 2000-04-19 EP disclosed
WO-2000001739-A1 CATALYST FOR THE POLYMERISATION OF OLEFINS BOREALIS TECHNOLOGY OY (FI) 2000-01-13 WO disclosed
WO-1998058001-A1 OLEFIN POLYMERIZATION PROCESS COCKBAIN, JULIAN (GB) 1998-12-23 WO disclosed