SCHEMBL6552149

SCHEMBL6552149

NP(N)(=O)Nc1nc(Cl)cc(Cl)n1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10932982 0.88 CYP2D6 (0.31)
SCHEMBL6553882 0.87 KMT2A (0.41)
SCHEMBL6553586 0.80 S1PR2 (0.34) S1PR2
SCHEMBL10931726 0.77 LMNA (0.38)
Hydrochloric Acid SCHEMBL11594641 0.76 TSHR (0.36)
SCHEMBL10935113 0.76
SCHEMBL6552161 0.74 GAA (0.41)
SCHEMBL30378441 0.69 S1PR2 (0.31) S1PR2
SCHEMBL28209707 0.69 S1PR2 (0.31) S1PR2
SCHEMBL6552483 0.68 KMT2A (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0329170-B1 Process for producing 2-amino-4,6-dichloropyrimidine ISHIHARA SANGYO KAISHA (JP) 1995-06-21 EP claimed
EP-1282628-B1 N-(2-PYRIMIDINYL)(THIO)PHOSPHORIC TRIAMIDES, METHOD FOR PRODUCING THE SAME, AND THE USE THEREOF AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC UREA HYDROLYSIS PIESTERITZ STICKSTOFF (DE) 2004-02-11 EP disclosed