SCHEMBL6552211

SCHEMBL6552211

COC(=O)C(N)CCSC.O[SiH](O)O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MARS1 P56192 8/20 0.41
METAP2 P50579 1/20 0.40
METAP1 P53582 1/20 0.40
ALDH1A1 P00352 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
CYP2C9 P11712 1/20 0.38
RNPEP Q9H4A4 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108559 0.94 MARS1 (0.44) MARS1METAP2METAP1ALDH1A1L3MBTL1
SCHEMBL108560 0.94 MARS1 (0.44) MARS1METAP2METAP1ALDH1A1L3MBTL1
SCHEMBL3089957 0.94 MARS1 (0.44) MARS1METAP2METAP1ALDH1A1L3MBTL1
Ammonia Solution, Strong SCHEMBL9081566 0.92 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL3089952 0.92 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL27980312 0.92 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrogen Sulfide SCHEMBL9171273 0.92 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL200899 0.92 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL200898 0.92 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL27980313 0.92 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1089704-B1 TRICHOLOGICAL LOTION FOR TOPICAL USE GECOMWERT ANSTALT (LI) 2004-02-11 EP disclosed
US-6479059-B2 A COSMETIC COMPOSITION TO REACTIVATE THE PHYSIOLOGICAL GROWTH OF HAIR; COMPRISING A SYNERGISTIC MIXTURE OF CYSTEINE OR DERIVATIVES, LYSINE OR DERIVATIVES AND A GLYCOPROTEIN IN A CARRIER; SIDE EFFECT REDUCTION; THICKENING GROWTH GECOMWERT ANSTALT (LI) 2002-11-12 US disclosed
US-20010003583-A1 Trichological lotion for topical use GECOMWERT ANSTALT 2001-06-14 US disclosed
EP-1089704-A1 TRICHOLOGICAL LOTION FOR TOPICAL USE Gecomwert Anstalt (LI) 2001-04-11 EP disclosed
WO-1999066887-A1 TRICHOLOGICAL LOTION FOR TOPICAL USE GECOMWERT ANSTALT (LI) 1999-12-29 WO disclosed