SCHEMBL3089957

SCHEMBL3089957

COC(=O)[C@H](N)CCSC

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MARS1 P56192 6/20 0.44
METAP2 P50579 1/20 0.43
METAP1 P53582 1/20 0.43
ALDH1A1 P00352 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
RNPEP Q9H4A4 1/20 0.41
CYP2C9 P11712 1/20 0.40
GAA P10253 1/20 0.39
ANPEP P15144 1/20 0.39
ENPEP Q07075 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108560 1.00 MARS1 (0.44) MARS1METAP2METAP1ALDH1A1L3MBTL1
SCHEMBL108559 1.00 MARS1 (0.44) MARS1METAP2METAP1ALDH1A1L3MBTL1
Ammonia Solution, Strong SCHEMBL9081566 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL3089952 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL200899 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrogen Sulfide SCHEMBL9171273 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL200898 0.98 MARS1 (0.43) MARS1METAP2METAP1ALDH1A1L3MBTL1
Sulfur Dioxide SCHEMBL28722439 0.96 MARS1 (0.42) MARS1METAP2METAP1ALDH1A1L3MBTL1
SCHEMBL6552211 0.94 MARS1 (0.41) MARS1METAP2METAP1ALDH1A1L3MBTL1
SCHEMBL28363177 0.93 ALDH1A1 (0.41) MARS1METAP2METAP1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113527399-B Ginsenoside CK derivative and application thereof in preparation of antitumor drugs 陕西巨子生物技术有限公司 2023-01-31 CN claimed
CN-113527399-A Ginsenoside CK derivative and application thereof in preparation of antitumor drugs 陕西巨子生物技术有限公司 2021-10-22 CN claimed
CN-118221675-A Electron transport material, preparation method and application thereof, solar cell and preparation method thereof 天合光能股份有限公司 2024-06-21 CN disclosed
CN-110707221-B Application of amino acid ionic liquid in preparation of perovskite layer in perovskite photoelectric device 北京大学深圳研究生院 2023-09-01 CN disclosed
CN-115043765-B Preparation of methionine derivative and its salt and use as gene carrier 黑龙江八一农垦大学 2023-08-15 CN disclosed
CN-113527399-B Ginsenoside CK derivative and application thereof in preparation of antitumor drugs 陕西巨子生物技术有限公司 2023-01-31 CN disclosed
CN-115043765-A Preparation of methionine derivative and salt thereof and application of methionine derivative and salt thereof as gene vector 黑龙江八一农垦大学 2022-09-13 CN disclosed
EP-3596052-B1 CHEMICAL COMPOUNDS NODTHERA LTD (GB) 2022-07-20 EP disclosed
US-11345669-B2 Urea derivatives and methods of use thereof NodThera Limited (GB) 2022-05-31 US disclosed
US-11345669-B2 Urea derivatives and methods of use thereof NodThera Limited (GB) 2022-05-31 US disclosed
CN-113527399-A Ginsenoside CK derivative and application thereof in preparation of antitumor drugs 陕西巨子生物技术有限公司 2021-10-22 CN disclosed
EP-0873123-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1998-10-28 EP disclosed
WO-1998032741-A1 INHIBITORS OF FARNESYL PROTEIN TRANSFERASE ZENECA LIMITED (GB) 1998-07-30 WO disclosed
WO-1997017070-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1997-05-15 WO disclosed
EP-0126974-B1 CARBOXYALKYL PEPTIDE DERIVATIVES G.D. Searle & Co. (US) 1988-06-15 EP disclosed
US-4568666-A COLLAGENASE INHIBITORS, ANTIARTJRITIC AGENTS G. D. SEARLE & CO. (US) 1986-02-04 US disclosed
US-4511504-A COLLAGENASE INHIBITORS G.D. SEARLE & CO. (US) 1985-04-16 US disclosed
EP-0126974-A1 Carboxyalkyl peptide derivatives G.D. Searle & Co. (US) 1984-12-05 EP disclosed
EP-0038046-B1 PHARMACEUTICAL AMIDES, AND PREPARATION, FORMULATIONS AND USE THEREOF THE WELLCOME FOUNDATION LIMITED (GB) 1984-02-29 EP disclosed
EP-0038046-A2 Pharmaceutical amides, and preparation, formulations and use thereof THE WELLCOME FOUNDATION LIMITED (GB) 1981-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345669-B2 Urea derivatives and methods of use thereof IL1B, IL1A, NOD1 MARS1 1374/4885METAP2 1644/4885METAP1 357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.