Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL10802180 | 0.96 | ALDH1A1 (0.41) | ALDH1A1MAPK1HIF1ATSHRERCC5 | |
| SCHEMBL6554182 | 0.96 | ALDH1A1 (0.41) | ALDH1A1MAPK1HIF1ATSHRERCC5 | |
| SCHEMBL3869293 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPK1HIF1ATSHRERCC5 | |
| SCHEMBL3859297 | 0.81 | TSHR (0.47) | ALDH1A1MAPK1HIF1ATSHRERCC5 | |
| SCHEMBL6552230 | 0.80 | TSHR (0.46) | ALDH1A1MAPK1HIF1ATSHRERCC5 | |
| SCHEMBL6554187 | 0.80 | TSHR (0.46) | ALDH1A1MAPK1HIF1ATSHRERCC5 | |
| SCHEMBL10802186 | 0.80 | TSHR (0.46) | ALDH1A1MAPK1HIF1ATSHRERCC5 | |
| Hydrochloric Acid SCHEMBL3869297 | 0.80 | TSHR (0.46) | ALDH1A1MAPK1HIF1ATSHRERCC5 | |
| Guanidine SCHEMBL9629187 | 0.75 | SMN1; SMN2 (0.41) | ALDH1A1MAPK1HIF1ATSHRERCC5 | |
| Guanidine SCHEMBL10792358 | 0.70 | FFAR1 (0.38) | ALDH1A1MAPK1HIF1ATSHRERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420083-B1 | EXCELLENT SENSITIVITY; DOES NOT REQUIRE WET DEVELOPMENT; HYDROPHILIC GROUPS IN POLYMER COORDINATE WITH THE POLYVALENT METAL CATION RELEASED BY HEAT AND FORM A HYDROPHOBIC POLYMER | FUJI PHOTO FILM CO., LTD. (JP) | 2002-07-16 | — | — | US | claimed |
| EP-1046496-A1 | Planographic printing plate precursor containing metal compounds, and process for producing planographic printing plates | FUJI PHOTO FILM CO., LTD. (JP) | 2000-10-25 | — | — | EP | claimed |
| EP-1046496-B1 | Planographic printing plate precursor containing metal compounds, and process for producing planographic printing plates | FUJI PHOTO FILM CO LTD (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-6420083-B1 | EXCELLENT SENSITIVITY; DOES NOT REQUIRE WET DEVELOPMENT; HYDROPHILIC GROUPS IN POLYMER COORDINATE WITH THE POLYVALENT METAL CATION RELEASED BY HEAT AND FORM A HYDROPHOBIC POLYMER | FUJI PHOTO FILM CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1046496-A1 | Planographic printing plate precursor containing metal compounds, and process for producing planographic printing plates | FUJI PHOTO FILM CO., LTD. (JP) | 2000-10-25 | — | — | EP | disclosed |