Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30323146 | 1.00 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL21847080 | 0.81 | KDM4E (0.51) | ALDH1A1L3MBTL1KMT2AKDM4EMAPT | |
| SCHEMBL21847072 | 0.80 | CMA1 (0.55) | SIGMAR1ALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL21847078 | 0.76 | USP2 (0.47) | ALDH1A1KMT2AKDM4EHTTLMNA | |
| SCHEMBL21847069 | 0.75 | KMT2A (0.43) | SIGMAR1ALDH1A1KMT2AMAPTTP53 | |
| SCHEMBL21847079 | 0.74 | KMT2A (0.48) | ALDH1A1KMT2AKDM4EHTTMAPT | |
| SCHEMBL21847082 | 0.73 | ALDH1A1 (0.42) | ALDH1A1KMT2AHTTMAPTMEN1 | |
| SCHEMBL21847077 | 0.73 | MEN1 (0.38) | ALDH1A1KMT2AKDM4EHTTMEN1 | |
| SCHEMBL25113752 | 0.72 | ALDH1A1 (0.43) | SIGMAR1ALDH1A1KMT2AHTTLMNA | |
| SCHEMBL21847076 | 0.71 | CYP11B1 (0.42) | ALDH1A1L3MBTL1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3639821-B1 | CARCINOGENESIS INHIBITOR | NAT CANCER CT (JP) | 2024-08-28 | — | — | EP | disclosed |
| US-11464762-B2 | Carcinogenesis inhibitor | NATIONAL CANCER CENTER (JP) | 2022-10-11 | — | — | US | disclosed |
| US-20200276163-A1 | CARCINOGENESIS INHIBITOR | NATIONAL CANCER CENTER (JP) | 2020-09-03 | — | — | US | disclosed |
| EP-3639821-A1 | CARCINOGENESIS INHIBITOR | National Cancer Center (JP) | 2020-04-22 | — | — | EP | disclosed |
| EP-1070706-B1 | Process for the preparation of 1-substituted 5-hydroxy-imidazolin-2,4-diones and 1-substituted 5-alkoxy-imidazolin-2,4-diones | BAYER CHEMICALS AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-6365752-B1 | REACTING GLYOXYLIC ACID AND AN N-SUBSTITUTED UREA IN AQUEOUS SOLUTION AND IN THE PRESENCE OF AN ACID CATALYST; EFFICIENCY; PURITY; NONTOXIC CHEMICAL INTERMEDIATES FOR DRUGS; INSECTICIDES; AMINO ACIDS AND TEXTILE ASSISTANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |
| EP-1070706-A1 | Process for the preparation of 1-substituted 5-hydroxy-imidazolin-2,4-diones and 1-substituted 5-alkoxy-imidazolin-2,4-diones | BAYER AG (DE) | 2001-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11464762-B2 | Carcinogenesis inhibitor | APC, MKI67, HRAS | SIGMAR1 3806/4885ALDH1A1 759/4885L3MBTL1 2642/4885 |
| US-20200276163-A1 | CARCINOGENESIS INHIBITOR | APC, MKI67, HRAS | SIGMAR1 3806/4885ALDH1A1 759/4885L3MBTL1 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.