Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MGLL | Q99685 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | IL18 | Q14116 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5945230 | 0.94 | HSD17B10 (0.58) | LMNAMAPTALDH1A1MGLLPOLB | |
| SCHEMBL6323128 | 0.89 | ELANE (0.49) | LMNAMAPTALDH1A1MGLLPOLB | |
| SCHEMBL6552544 | 0.89 | MAOA (0.50) | LMNAMAPTALDH1A1MGLLPOLB | |
| SCHEMBL11125066 | 0.89 | MAPT (0.55) | LMNAMAPTALDH1A1MGLLPOLB | |
| SCHEMBL14878264 | 0.85 | MEN1 (0.50) | LMNAMAPTALDH1A1MGLLPOLB | |
| SCHEMBL2163500 | 0.85 | PARP15 (0.52) | LMNAMAPTALDH1A1MGLLPOLB | |
| SCHEMBL6670976 | 0.84 | MAPT (0.53) | LMNAMAPTALDH1A1MGLLPOLB | |
| SCHEMBL18087020 | 0.83 | CA12 (0.50) | LMNAMAPTALDH1A1POLBF2 | |
| Hydrochloric Acid SCHEMBL11852417 | 0.83 | MMP2 (0.50) | LMNAMAPTALDH1A1MGLLPOLB | |
| SCHEMBL10500433 | 0.83 | MAPT (0.49) | LMNAMAPTALDH1A1MGLLCUL4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8218291-B2 | Monomers for preparing polycarbonate resins, methods of preparing the monomers, polycarbonate resins prepared with the monomers, and capacitors comprising the polycarbonate resins | GENERAL ELECTRIC COMPANY (US) | 2012-07-10 | — | — | US | claimed |
| US-20110242729-A1 | Monomers for preparing polycarbonate resins, methods of preparing the monomers, polycarbonate resins prepared with the monomers, and capacitors comprising the polycarbonate resins | GENERAL ELECTRIC COMPANY (US) | 2011-10-06 | — | — | US | claimed |
| US-4212989-A | ARYL ESTER SOLVENTS USED IN CATALYTIC CARBONYLATION FO ALCOHOLS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-07-15 | — | — | US | claimed |
| US-12161114-B2 | Overpowered ABA receptor agonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-12-10 | — | — | US | disclosed |
| CN-118955398-A | Benzimidazole derivative corrosion inhibitor and preparation method thereof | 天津新翔油气技术有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118076767-A | Method and formulation for producing an optical metal oxide layer | 默克专利有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117120419-A | KLK5 bicyclic heteroaromatic inhibitors | 拜奥克里斯特制药公司 | 2023-11-24 | — | — | CN | disclosed |
| US-20230174541-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | VITAE PHARMACEUTICALS, LLC | 2023-06-08 | — | — | US | disclosed |
| US-11479557-B2 | Inhibitors of the menin-MLL interaction | VITAE PHARMACEUTICALS, LLC (US) | 2022-10-25 | — | — | US | disclosed |
| US-20210112808-A1 | OVERPOWERED ABA RECEPTOR AGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-04-22 | — | — | US | disclosed |
| EP-3383970-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2021-03-31 | — | — | EP | disclosed |
| EP-0622690-A1 | Electrostatic image developing toner | HODOGAYA CHEMICAL CO., LTD. (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-4735959-A | HYPOGLYCEMIC AGENTS | DR. KARL THOMAE GMBH (DE) | 1988-04-05 | — | — | US | disclosed |
| EP-0087298-B1 | PROCESS FOR PRODUCING BENZALDEHYDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-05-28 | — | — | EP | disclosed |
| US-4500721-A | Process for producing benzaldehydes | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1985-02-19 | — | — | US | disclosed |
| EP-0087298-A2 | Process for producing benzaldehydes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-08-31 | — | — | EP | disclosed |
| US-4381221-A | Process for recovering a reaction product while preventing decomposition of the catalyst | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1983-04-26 | — | — | US | disclosed |
| US-4234733-A | PHENOL, ALIPHATIC ESTER OR ETHER, CARBON MONOXIDE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-11-18 | — | — | US | disclosed |
| US-4212989-A | ARYL ESTER SOLVENTS USED IN CATALYTIC CARBONYLATION FO ALCOHOLS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-07-15 | — | — | US | disclosed |
| US-3975537-A | SUBSTITUTED BENZOFURANS | SMITH KLINE (US) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174541-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | MLLT1, MEN1, MLLT3 | LMNA 873/4885MAPT 1447/4885ALDH1A1 4369/4885 |
| US-20110242729-A1 | Monomers for preparing polycarbonate resins, methods of preparing the monomers, polycarbonate resins prepared with the monomers, and capacitors comprising the polycarbonate resins | JMJD1C, TET1, MECP2 | LMNA 891/4885MAPT 685/4885ALDH1A1 4094/4885 |
| US-20210112808-A1 | OVERPOWERED ABA RECEPTOR AGONISTS | BROX, AVPR1A, NPBWR1 | LMNA 4640/4885MAPT 4266/4885ALDH1A1 3237/4885 |
| US-12161114-B2 | Overpowered ABA receptor agonists | BROX, AVPR1A, NPBWR1 | LMNA 4640/4885MAPT 4266/4885ALDH1A1 3237/4885 |
| US-11479557-B2 | Inhibitors of the menin-MLL interaction | MLLT1, MEN1, MLLT3 | LMNA 873/4885MAPT 1447/4885ALDH1A1 4369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.