Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.57 |
| ▸ | PPARG | P37231 | 7/20 | 0.57 |
| ▸ | PPARD | Q03181 | 7/20 | 0.57 |
| ▸ | PPARA | Q07869 | 7/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | FABP4 | P15090 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL6550913 | 0.88 | LMNA (0.69) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Sebacic Acid SCHEMBL28243888 | 0.88 | TSHR (0.75) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL6550920 | 0.88 | LMNA (0.69) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL6552701 | 0.88 | LMNA (0.69) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL23533535 | 0.85 | LMNA (0.65) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Sebacic Acid SCHEMBL6551847 | 0.85 | TSHR (0.71) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL27845078 | 0.85 | LMNA (0.65) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL27756650 | 0.85 | LMNA (0.65) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL6402459 | 0.85 | LMNA (0.65) | LMNATSHRNFKB1PMP22AKR1B1 | |
| Adipic Acid SCHEMBL874846 | 0.85 | LMNA (0.65) | LMNATSHRNFKB1PMP22AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11160734-B2 | Personal care compositions comprising shaped abrasive particles | THE PROCTER & GAMBLE COMPANY (US) | 2021-11-02 | — | — | US | disclosed |
| EP-2720666-B1 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | PROCTER & GAMBLE (US) | 2019-03-20 | — | — | EP | disclosed |
| US-20170312190-A1 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | PROCTER & GAMBLE (US) | 2017-11-02 | — | — | US | disclosed |
| US-9675531-B2 | Personal care compositions comprising shaped abrasive particles | THE PROCTER & GAMBLE COMPANY (US) | 2017-06-13 | — | — | US | disclosed |
| US-8759270-B2 | Liquid detergent composition with abrasive particles | THE PROCTER & GAMBLE COMPANY (US) | 2014-06-24 | — | — | US | disclosed |
| EP-2720666-A2 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | The Procter and Gamble Company (US) | 2014-04-23 | — | — | EP | disclosed |
| US-8546316-B2 | Liquid detergent composition with natural abrasive particles | THE PROCTER & GAMBLE COMPANY (US) | 2013-10-01 | — | — | US | disclosed |
| EP-2561055-A1 | LIQUID CLEANING AND/OR CLEANSING COMPOSITION | The Procter & Gamble Company (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-2561056-A1 | LIQUID CLEANING AND/OR CLEANSING COMPOSITION | The Procter & Gamble Company (US) | 2013-02-27 | — | — | EP | disclosed |
| US-20130039961-A1 | Personal Care Compositions Comprising Shaped Abrasive Particles | THE PROCTER & GAMBLE COMPANY | 2013-02-14 | — | — | US | disclosed |
| WO-2012177629-A2 | LIQUID DETERGENT COMPOSITION WITH ABRASIVE PARTICLES | THE PROCTER & GAMBLE COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| EP-2537917-A1 | Liquid detergent composition with abrasive particles | The Procter & Gamble Company (US) | 2012-12-26 | — | — | EP | disclosed |
| US-20120322713-A1 | LIQUID DETERGENT COMPOSITION WITH ABRASIVE PARTICLES | THE PROCTER & GAMBLE COMPANY | 2012-12-20 | — | — | US | disclosed |
| WO-2012040314-A1 | LIQUID DETERGENT COMPOSITION WITH ABRASIVE PARTICLES | THE PROCTER & GAMBLE COMPANY (US) | 2012-03-29 | — | — | WO | disclosed |
| US-20120071383-A1 | LIQUID DETERGENT COMPOSITION WITH ABRASIVE PARTICLES | THE PROCTER & GAMBLE COMPANY | 2012-03-22 | — | — | US | disclosed |
| EP-2431451-A1 | Liquid detergent composition with abrasive particles | The Procter & Gamble Company (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2011133438-A1 | LIQUID CLEANING AND/OR CLEANSING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2011-10-27 | — | — | WO | disclosed |
| WO-2011133508-A1 | LIQUID CLEANING AND/OR CLEANSING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2011-10-27 | — | — | WO | disclosed |
| US-20110262504-A1 | LIQUID CLEANING AND/OR CLEANSING COMPOSITION | THE PROCTER & GAMBLE COMPANY | 2011-10-27 | — | — | US | disclosed |
| US-20110262371-A1 | LIQUID CLEANING AND/OR CLEANSING COMPOSITION | THE PROCTER & GAMBLE COMPANY | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170312190-A1 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | POLR1C, PLOD3, C9 | LMNA 194/4885TSHR 3873/4885NFKB1 2522/4885 |
| US-11160734-B2 | Personal care compositions comprising shaped abrasive particles | POLR1C, PLOD3, C9 | LMNA 194/4885TSHR 3873/4885NFKB1 2522/4885 |
| US-20110262371-A1 | LIQUID CLEANING AND/OR CLEANSING COMPOSITION | APOBEC3G, APOBEC3C, EXOSC9 | LMNA 1746/4885TSHR 4324/4885NFKB1 3944/4885 |
| US-20110262504-A1 | LIQUID CLEANING AND/OR CLEANSING COMPOSITION | APOBEC3G, APOBEC3C, EXOSC9 | LMNA 1746/4885TSHR 4324/4885NFKB1 3944/4885 |
| US-20130039961-A1 | Personal Care Compositions Comprising Shaped Abrasive Particles | POLR1C, PLOD3, C9 | LMNA 194/4885TSHR 3873/4885NFKB1 2522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.