Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124046 | 0.92 | MTNR1A (0.47) | MTNR1AMTNR1BHTR2ATRPV1HTR2C | |
| SCHEMBL1180547 | 0.89 | MTNR1A (0.44) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL5088679 | 0.86 | DRD2 (0.36) | — | |
| SCHEMBL5369468 | 0.84 | DRD2 (0.36) | — | |
| SCHEMBL8016986 | 0.84 | HTR1A (0.42) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL30344940 | 0.84 | DRD2 (0.36) | — | |
| SCHEMBL6099019 | 0.82 | ALDH1A1 (0.44) | MTNR1AMTNR1BHTR2ASMN1; SMN2 | |
| SCHEMBL6101788 | 0.80 | ALDH1A1 (0.44) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL30203278 | 0.80 | ALDH1A1 (0.44) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL8499741 | 0.79 | KDM4E (0.49) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409476-B1 | PHARMACEUTICAL COMPOUNDS WITH SEROTONIN RECEPTOR ACTIVITY | LILLY CO ELI (US) | 2004-12-15 | — | — | EP | disclosed |