Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6553935 | 0.87 | NPC1 (0.38) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL3012217 | 0.83 | NPC1 (0.33) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL10320383 | 0.82 | PNMT (0.41) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL3006683 | 0.81 | NPC1 (0.31) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2999082 | 0.80 | NPC1 (0.31) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL139575 | 0.80 | NPC1 (0.31) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3005948 | 0.80 | DRD2 (0.31) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7101940 | 0.78 | NPC1 (0.35) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL138704 | 0.78 | NPC1 (0.33) | NPC1RAB9APNMT | |
| Hydrochloric Acid SCHEMBL8858052 | 0.78 | CES2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773237-B1 | Olefin polymerization catalyst system | MITSUI CHEMICALS INC (JP) | 2004-02-18 | — | — | EP | disclosed |