Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL873040 | 0.89 | POLB (0.38) | BBOX1ALDH1A1TSHRPOLBBLM | |
| Acrylic Acid SCHEMBL1713956 | 0.89 | BBOX1 (0.43) | BBOX1ALDH1A1TSHRPOLBBLM | |
| Methacrylic Acid SCHEMBL8154112 | 0.89 | ALDH1A1 (0.41) | BBOX1ALDH1A1TSHRPOLBBLM | |
| Methacrylic Acid SCHEMBL540788 | 0.87 | CA4 (0.38) | BBOX1POLBBLMATMMEN1 | |
| Acrylic Acid SCHEMBL3810916 | 0.87 | BBOX1 (0.44) | BBOX1ALDH1A1TSHRMEN1CYP1A2 | |
| Acrylic Acid SCHEMBL1713958 | 0.85 | BBOX1 (0.43) | BBOX1ALDH1A1TSHRMEN1CYP1A2 | |
| Methacrylic Acid SCHEMBL873041 | 0.85 | CA4 (0.36) | BBOX1POLBBLMATMMEN1 | |
| Methacrylic Acid SCHEMBL7941570 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| Methacrylic Acid SCHEMBL20954075 | 0.80 | ALDH1A1 (0.45) | ALDH1A1TSHR | |
| Methacrylic Acid SCHEMBL20954078 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940136-B1 | Reducing agent from a plurality of components and process for permanent hair waving using it | OREAL (FR) | 2004-10-13 | — | — | EP | claimed |
| EP-0930061-B1 | Oxidizing agent from a plurality of components and process for permanent hair waving using it | OREAL (FR) | 2004-02-25 | — | — | EP | claimed |
| US-6238658-B1 | THICKENING POLYMER BEING IN THE FORM OF AN AQUEOUS DISPERSION, AN OILY DISPERSION, OR AS A REVERSE EMULSION, WITH THE PROVISO THAT SAID THICKENING POLYMER IS NOT QUATERNARY HYDROXYETHYLCELLULOSE | L'OREAL S.A. (FR) | 2001-05-29 | — | — | US | claimed |
| US-6187302-B1 | THIOL-BEARING REDUCING AGENT IN AQUEOUS MEDIUM, AND AT LEAST ONE THICKENING POLYMER IN AQUEOUS MEDIUM, SAID THICKENING POLYMER BEING IN THE FORM OF AN AQUEOUS DISPERSION, AN OILY DISPERSION, OR A REVERSE EMULSION | L'OREAL S.A. (FR) | 2001-02-13 | — | — | US | claimed |
| US-6238658-B1 | THICKENING POLYMER BEING IN THE FORM OF AN AQUEOUS DISPERSION, AN OILY DISPERSION, OR AS A REVERSE EMULSION, WITH THE PROVISO THAT SAID THICKENING POLYMER IS NOT QUATERNARY HYDROXYETHYLCELLULOSE | L'OREAL S.A. (FR) | 2001-05-29 | — | — | US | disclosed |
| US-6187302-B1 | THIOL-BEARING REDUCING AGENT IN AQUEOUS MEDIUM, AND AT LEAST ONE THICKENING POLYMER IN AQUEOUS MEDIUM, SAID THICKENING POLYMER BEING IN THE FORM OF AN AQUEOUS DISPERSION, AN OILY DISPERSION, OR A REVERSE EMULSION | L'OREAL S.A. (FR) | 2001-02-13 | — | — | US | disclosed |