Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL540788 | 0.97 | CA4 (0.38) | POLBBLMATMCA4BBOX1 | |
| Methacrylic Acid SCHEMBL873041 | 0.95 | CA4 (0.36) | POLBBLMATMCA4BBOX1 | |
| Methacrylic Acid SCHEMBL6553565 | 0.89 | BBOX1 (0.36) | POLBBLMATMBBOX1MEN1 | |
| Methacrylic Acid SCHEMBL8154112 | 0.86 | ALDH1A1 (0.41) | POLBBLMATMBBOX1ALDH1A1 | |
| Methacrylic Acid SCHEMBL28377504 | 0.85 | BBOX1 (0.45) | CA4BBOX1ALDH1A1CA1TDP1 | |
| Methacrylic Acid SCHEMBL4924752 | 0.85 | BBOX1 (0.45) | CA4BBOX1ALDH1A1CYP2C19THRB | |
| Methacrylic Acid SCHEMBL5175782 | 0.84 | CHRM5 (0.39) | POLBBLMATMBBOX1CYP2C19 | |
| Methacrylic Acid SCHEMBL17453351 | 0.83 | TDP1 (0.38) | CA4BBOX1CA1TDP1 | |
| Tetrylammonium SCHEMBL2347482 | 0.82 | TSHR (0.42) | ATMCA4BBOX1ALDH1A1THRB | |
| Methacrylic Acid SCHEMBL2059649 | 0.82 | ALDH1A1 (0.42) | POLBBLMATMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912644-A | Amphiphilic sizing agent applicable to glass fiber/resin composite material | 宁波维创柔性电子技术有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119072297-A | Microcapsules and methods | 联合利华知识产权控股有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-116589897-A | Stone-like paint and preparation process thereof | 湖北普耐新型建材有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-112041361-B | Stabilized polyurea microcapsule compositions | 国际香料和香精公司 | 2023-06-30 | — | — | CN | claimed |
| CN-113438939-A | Protein microcapsule and preparation method thereof | 国际香料和香精公司 | 2021-09-24 | — | — | CN | claimed |
| WO-2021130532-A1 | PROCESS FOR PRODUCING A PHARMACEUTICAL COMPOSITION CONTAINING MICRO PARTICLES | SUNSTAR INC. (JP) | 2021-07-01 | — | — | WO | claimed |
| US-20210196636-A1 | PROCESS FOR PRODUCING A PHARMACEUTICAL COMPOSITION CONTAINING MICRO PARTICLES | SUNSTAR INC. (JP) | 2021-07-01 | — | — | US | claimed |
| US-20150133577-A1 | VINYL ACETATE-ETHYLENE COPOLYMER EMULSION AND PAPER COATING COMPOSITION BASED ON THE SAME | CELANESE INTERNATIONAL CORPORATION (US) | 2015-05-14 | — | — | US | claimed |
| EP-2850141-A1 | VINYL ACETATE-ETHYLENE COPOLYMER EMULSION AND PAPER COATING COMPOSITION BASED ON THE SAME | Celanese International Corporation (US) | 2015-03-25 | — | — | EP | claimed |
| WO-2014071550-A1 | VINYL ACETATE-ETHYLENE COPOLYMER EMULSION AND BINDER COMPOSITION FOR TEXTILE LAMINATION APPLICATIONS BASED ON THE SAME | CELANESE INTERNATIONAL CORPORATION (US) | 2014-05-15 | — | — | WO | claimed |
| WO-2009063042-A1 | THICKENED REDUCING COMPOSITION | L'OREAL (FR) | 2009-05-22 | — | — | WO | claimed |
| CN-1216642-C | Anti-infective active substance combinations and use thereof for topical treatment of fungus diseases of toe and finger nails | AVENTIS PHARMA GMBH (DE) | 2005-08-31 | — | — | CN | claimed |
| EP-0940136-B1 | Reducing agent from a plurality of components and process for permanent hair waving using it | OREAL (FR) | 2004-10-13 | — | — | EP | claimed |
| EP-0930061-B1 | Oxidizing agent from a plurality of components and process for permanent hair waving using it | OREAL (FR) | 2004-02-25 | — | — | EP | claimed |
| CN-1416353-A | Anti-infective active substance combinations and use thereof for topical treatment of fungus diseases of toe and finger nails | AVENTIS PHARMA GMBH (DE) | 2003-05-07 | — | — | CN | claimed |
| US-6238658-B1 | THICKENING POLYMER BEING IN THE FORM OF AN AQUEOUS DISPERSION, AN OILY DISPERSION, OR AS A REVERSE EMULSION, WITH THE PROVISO THAT SAID THICKENING POLYMER IS NOT QUATERNARY HYDROXYETHYLCELLULOSE | L'OREAL S.A. (FR) | 2001-05-29 | — | — | US | claimed |
| US-6187302-B1 | THIOL-BEARING REDUCING AGENT IN AQUEOUS MEDIUM, AND AT LEAST ONE THICKENING POLYMER IN AQUEOUS MEDIUM, SAID THICKENING POLYMER BEING IN THE FORM OF AN AQUEOUS DISPERSION, AN OILY DISPERSION, OR A REVERSE EMULSION | L'OREAL S.A. (FR) | 2001-02-13 | — | — | US | claimed |
| EP-0635265-B1 | Controlled release pharmaceutical compositions based on one or more pharmaceutically acceptable salts of gamma hydroxy-butyric acid | CT LAB FARM SRL (IT) | 2000-02-02 | — | — | EP | claimed |
| EP-0550295-B1 | Process for the preparation of paper and paper laminates. | RHODIA CHIMIE SA (FR) | 1998-05-27 | — | — | EP | claimed |
| EP-0635265-A1 | Controlled release pharmaceutical compositions based on one or more pharmaceutically acceptable salts of gamma hydroxy-butyric acid | LABORATORIO FARMACEUTICO C.T. S.r.l. (IT) | 1995-01-25 | — | — | EP | claimed |