Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 4/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.37 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239576 | 0.75 | TSHR (0.34) | SMPD1FDPSPLA2G2ALPAR3 | |
| SCHEMBL4068245 | 0.75 | SMPD1 (0.47) | SMPD1FDPSLAP3SGPL1LPAR1 | |
| SCHEMBL9492034 | 0.73 | FDPS (0.45) | SMPD1FDPSLAP3SGPL1LPAR1 | |
| SCHEMBL2962258 | 0.69 | FAAH (0.47) | LPAR1LPAR3LPAR2 | |
| SCHEMBL11466053 | 0.68 | FAAH (0.53) | LPAR3LPAR2 | |
| SCHEMBL11094630 | 0.68 | FAAH (0.53) | LPAR3LPAR2 | |
| SCHEMBL10447327 | 0.67 | FDPS (0.59) | SMPD1FDPSLAP3LPAR3LPAR2 | |
| SCHEMBL10876126 | 0.67 | FDPS (0.65) | SMPD1FDPSLAP3LPAR3LPAR2 | |
| SCHEMBL1259333 | 0.67 | FDPS (0.65) | SMPD1FDPSLAP3LPAR3LPAR2 | |
| SCHEMBL2251269 | 0.67 | FDPS (0.65) | SMPD1FDPSLAP3LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485391-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003080630-A2 | PHOSPHATE TRANSPORT INHIBITORS | GENZYME CORPORATION (US) | 2003-10-02 | — | — | WO | disclosed |