Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
| ▸ | FDPS | P14324 | 3/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2963056 | 0.79 | TSHR (0.41) | TSHRPLA2G2CSMPD1FDPSLPAR3 | |
| SCHEMBL2960728 | 0.77 | TSHR (0.39) | TSHRPLA2G2CSMPD1FDPSLPAR3 | |
| SCHEMBL6553653 | 0.75 | SMPD1 (0.39) | PLA2G2ASMPD1FDPSLPAR3 | |
| SCHEMBL13239578 | 0.71 | TSHR (0.40) | TSHRFDPSLPAR3 | |
| SCHEMBL13239577 | 0.70 | FDPS (0.46) | TSHRSMPD1FDPSLPAR3 | |
| SCHEMBL2961043 | 0.68 | TSHR (0.42) | TSHRFDPSLPAR3 | |
| SCHEMBL2954338 | 0.67 | LPAR3 (0.39) | TSHRLPAR3 | |
| SCHEMBL2963060 | 0.66 | SMPD1 (0.42) | TSHRPLA2G2CSMPD1FDPS | |
| SCHEMBL6741682 | 0.64 | LPAR3 (0.44) | LPAR3 | |
| SCHEMBL2962258 | 0.64 | FAAH (0.47) | LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754200-B2 | Phosphate transport inhibitors | GENZYME CORPORATION (US) | 2010-07-13 | — | — | US | disclosed |