SCHEMBL6553722

SCHEMBL6553722

CCCCN(CCC#N)c1cc[c]cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 2/20 0.41
TSHR P16473 2/20 0.39
SLC16A3 O15427 2/20 0.37
SLC16A1 P53985 2/20 0.37
EGFR P00533 1/20 0.35
ERBB2 P04626 1/20 0.35
HPGD P15428 2/20 0.34
MAPT P10636 2/20 0.34
DRD3 P35462 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ALDH1A1 P00352 1/20 0.33
AR P10275 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11329200 0.89 CRHR1 (0.39) CRHR1TSHRHPGDMAPTDRD3
SCHEMBL126299 0.89 EGFR (0.40) SLC16A3SLC16A1EGFRERBB2MAPT
SCHEMBL6554137 0.87 TSHR (0.40) TSHRHPGDMEN1KMT2AALDH1A1
SCHEMBL9323694 0.86 HSD17B10 (0.44) CRHR1TSHRSLC16A3SLC16A1HPGD
SCHEMBL4719828 0.85 EGFR (0.38) SLC16A3SLC16A1EGFRERBB2MAPT
SCHEMBL6555127 0.84 ALDH1A1 (0.38) CRHR1TSHRHPGDMAPTDRD3
SCHEMBL1080080 0.83 EGFR (0.36) SLC16A3SLC16A1EGFRERBB2AR
SCHEMBL7452206 0.83 CYP3A4 (0.47) CRHR1TSHRSLC16A3SLC16A1EGFR
SCHEMBL9800597 0.82 DNM1 (0.38) EGFRERBB2CNR2
SCHEMBL9800564 0.82 DNM1 (0.38) EGFRERBB2CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1234007-B1 OLIGOMERIC METHINE DYES CLARIANT FINANCE BVI LTD (VG) 2004-02-18 EP disclosed
EP-1234007-A1 OLIGOMERIC METHINE DYES Clariant Finance (BVI) Limited (VG) 2002-08-28 EP disclosed
WO-2001036543-A1 OLIGOMERIC METHINE DYES CLARIANT FINANCE (BVI) LIMITED (VG) 2001-05-25 WO disclosed
US-4256458-A DIMERIC PYRIDINIUM DYES BASF AKTIENGESELLSCHAFT (DE) 1981-03-17 US disclosed