Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719828 | 0.96 | EGFR (0.38) | EGFRERBB2ARCNR2CHRM2 | |
| SCHEMBL1080080 | 0.94 | EGFR (0.36) | EGFRERBB2ARCNR2CHRM2 | |
| SCHEMBL9800564 | 0.92 | DNM1 (0.38) | EGFRERBB2CNR2 | |
| SCHEMBL9800597 | 0.92 | DNM1 (0.38) | EGFRERBB2CNR2 | |
| SCHEMBL2456296 | 0.92 | ALDH1A1 (0.38) | EGFRERBB2ARCNR2CHRM2 | |
| SCHEMBL2460601 | 0.92 | DNM1 (0.38) | EGFRERBB2CNR2 | |
| SCHEMBL6553722 | 0.89 | CRHR1 (0.41) | EGFRERBB2ARCNR2KDM4E | |
| SCHEMBL128995 | 0.86 | EGFR (0.37) | EGFRERBB2ARCNR2KDM4E | |
| SCHEMBL2459645 | 0.84 | CNR2 (0.42) | CNR2KDM4ETDP1 | |
| SCHEMBL7153351 | 0.84 | EGFR (0.50) | EGFRERBB2ARCNR2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141391-B | Ethylene-polar styrene quasi-random copolymer and preparation method thereof | 中国科学院长春应用化学研究所 | 2020-03-13 | — | — | CN | claimed |
| EP-3386952-A1 | SUBSTITUTED BENZIMIDAZOLIUM, PYRIDO-IMIDAZOLIUM, OR PYRAZINO-IMIDAZOLIUM COMPOUNDS AS CHEMOTHERAPEUTICS | The Board of Regents of The University of Texas System (US) | 2018-10-17 | — | — | EP | claimed |
| WO-2017100525-A1 | SUBSTITUTED BENZIMIDAZOLIUM, PYRIDO-IMIDAZOLIUM, OR PYRAZINO-IMIDAZOLIUM COMPOUNDS AS CHEMOTHERAPEUTICS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-06-15 | — | — | WO | claimed |
| CN-103946922-A | Photorefractive composite | UNIV MUENSTER WILHELMS | 2014-07-23 | — | — | CN | claimed |
| CN-101613321-A | The list and the bicyclic pyrrole derivatives that suppress part and advanced glycation end product acceptor interaction | TRANSTECH PHARMA INC | 2009-12-30 | — | — | CN | claimed |
| CN-101505751-A | 8-hydroxyquinoline compounds and methods thereof | WYETH CORP (US) | 2009-08-12 | — | — | CN | claimed |
| CN-1633290-A | Mono-and bicyclic pyrrole derivatives inhibiting ligand interaction with higher glycation end product receptors | TRANSTECH PHARMA INC (US) | 2005-06-29 | — | — | CN | claimed |
| US-6884815-B1 | High affinity small molecule C5a receptor modulators | NEUROGEN CORPORATION (US) | 2005-04-26 | — | — | US | claimed |
| EP-1482931-A2 | MONO- AND BICYCLIC AZOLE DERIVATIVES THAT INHIBIT THE INTERACTION OF LIGANDS WITH RAGE | Transtech Pharma, Inc. (US) | 2004-12-08 | — | — | EP | claimed |
| US-20040082542-A1 | Azole derivatives and fused bicyclic azole derivatives as therapeutic agents | VTV THERAPEUTICS LLC | 2004-04-29 | — | — | US | claimed |
| WO-2003075921-A2 | MONO- AND BICYCLIC AZOLE DERIVATIVES THAT INHIBIT THE INTERACTION OF LIGANDS WITH RAGE | TRANSTECH PHARMA, INC. (US) | 2003-09-18 | — | — | WO | claimed |
| EP-0884367-B1 | Light-writable data storage media containing cationic diphenylamine dyes | BAYER AG (DE) | 2003-08-13 | — | — | EP | claimed |
| US-5952475-A | CATIONIC THIADIAZOLEDIPHENYLAMINE DYES FOR USE IN INKJET PRINTING AND IN LIGHT-WRITABLE DATA STORAGE MEDIA AND IN DYE TRANSFER FILMS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-14 | — | — | US | claimed |
| EP-0884367-A2 | Cationic diphenylamine dyestuffs and their anhydrobases | BAYER AG (DE) | 1998-12-16 | — | — | EP | claimed |
| US-4454211-A | Electrophotographic photosensitive member with pyrazoline charge transport material | CANON KABUSHIKI KAISHA (JP) | 1984-06-12 | — | — | US | claimed |
| US-4420548-A | Electrophotographic member with hydrazone or ketazine compounds | CANON KABUSHIKI KAISHA (JP) | 1983-12-13 | — | — | US | claimed |
| US-20220404729-A1 | TONER PARTICLES FOR DEVELOPING ELECTROSTATICALLY CHARGED IMAGE AND TONER COMPOSITION FOR DEVELOPING ELECTROSTATICALLY CHARGED IMAGE | TOMOEGAWA CORPORATION (JP) | 2022-12-22 | — | — | US | disclosed |
| CN-110461951-B | Composition, dichroic material, light-absorbing anisotropic film, laminate, and image display device | 富士胶片株式会社 | 2022-04-08 | — | — | CN | disclosed |
| US-4008330-A | A P-AMINOPHENYL-THIOUREA | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1977-02-15 | — | — | US | disclosed |
| US-3936462-A | CNS DEPRESSANT, ANALGESIC | STERLING DRUG INC. (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082542-A1 | Azole derivatives and fused bicyclic azole derivatives as therapeutic agents | AGER, S100A4, S100B | EGFR 108/4885ERBB2 209/4885AR 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.