Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30023393 | 0.84 | CYP2C19 (0.56) | POLBSIGMAR1MEN1KMT2AALDH1A1 | |
| Histapyrrodine SCHEMBL142300 | 0.77 | SIGMAR1 (0.54) | SIGMAR1MEN1KMT2AALDH1A1LMNA | |
| Histapyrrodine SCHEMBL316865 | 0.76 | SIGMAR1 (0.53) | SIGMAR1MEN1KMT2AALDH1A1LMNA | |
| Histapyrrodine SCHEMBL1651354 | 0.75 | SIGMAR1 (0.51) | SIGMAR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2103973 | 0.74 | CYP2C19 (0.59) | KMT2AALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL17346437 | 0.73 | MAPK1 (0.47) | POLBSIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL4470439 | 0.71 | DRD3 (0.36) | POLBSIGMAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7565830 | 0.71 | CHRM2 (0.53) | ALDH1A1LMNAKDM4EMAPTMAPK1 | |
| SCHEMBL6555348 | 0.71 | POLB (0.48) | POLBKMT2AALDH1A1LMNATSHR | |
| SCHEMBL28276177 | 0.70 | LMNA (0.55) | SIGMAR1MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1234007-B1 | OLIGOMERIC METHINE DYES | CLARIANT FINANCE BVI LTD (VG) | 2004-02-18 | — | — | EP | disclosed |
| US-4256458-A | DIMERIC PYRIDINIUM DYES | BASF AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |