Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22784012 | 0.90 | ALDH1A1 (0.44) | ALDH1A1ATMHTR2CP2RX4KMT2A | |
| SCHEMBL9880595 | 0.80 | HTR2C (0.48) | ALDH1A1HTR2CP2RX4KMT2AMEN1 | |
| SCHEMBL20173266 | 0.76 | HTR2C (0.45) | ALDH1A1HTR2CP2RX4KMT2AMEN1 | |
| SCHEMBL2837955 | 0.76 | SLC7A5 (0.48) | P2RX4KMT2AMEN1SMN1; SMN2SLC15A1 | |
| SCHEMBL7167346 | 0.76 | FAAH (0.48) | ALDH1A1HTR2CP2RX4KMT2AMEN1 | |
| SCHEMBL10887553 | 0.71 | CTSB (0.37) | ALDH1A1HTR2CP2RX4KMT2AMEN1 | |
| SCHEMBL28935982 | 0.71 | NR1H2 (0.41) | ALDH1A1HTR2CP2RX4KMT2AMEN1 | |
| SCHEMBL29203797 | 0.70 | HTR2C (0.39) | ALDH1A1HTR2CP2RX4KMT2AMEN1 | |
| SCHEMBL323456 | 0.70 | ALDH1A1 (0.52) | ALDH1A1HTR2CP2RX4KMT2AMEN1 | |
| SCHEMBL1170984 | 0.69 | ALDH1A1 (0.55) | ALDH1A1HTR2CP2RX4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708179-B1 | Glucagon-like insulinotropic peptide analogs, compositions, and methods of use | LILLY CO ELI (US) | 2004-12-22 | — | — | EP | disclosed |
| US-5512549-A | ANTIDIABETIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0708179-A2 | Glucagon-like insulinotropic peptide analogs, compositions, and methods of use | ELI LILLY AND COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |