Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554230 | 0.91 | MTNR1A (0.44) | POLBMAPTPKMMTNR1AMTNR1B | |
| SCHEMBL6540614 | 0.90 | MTNR1A (0.54) | PKMMTNR1AMTNR1BTRPV1NQO2 | |
| SCHEMBL6540852 | 0.85 | ALDH1A1 (0.51) | MTNR1AMTNR1BTRPV1PTPRCPTPN1 | |
| SCHEMBL6540686 | 0.81 | MTNR1A (0.43) | MTNR1AMTNR1BTRPV1KMT2AMEN1 | |
| SCHEMBL6539895 | 0.77 | KMT2A (0.49) | MAPTPKMMTNR1AMTNR1BKMT2A | |
| SCHEMBL6541141 | 0.75 | NLRP3 (0.49) | KMT2AMEN1 | |
| SCHEMBL6554075 | 0.74 | KMT2A (0.45) | POLBMAPTPKMTRPV1KMT2A | |
| SCHEMBL6677713 | 0.74 | CA1 (0.43) | MAPTKMT2AMEN1CACNA1BAPBA1 | |
| SCHEMBL6540276 | 0.74 | CA1 (0.55) | MAPTABCB11 | |
| SCHEMBL6677005 | 0.74 | TSHR (0.47) | POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |