Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.60 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.60 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141197 | 0.83 | EP300 (0.65) | EP300KAT2BKAT8KEAP1KDM4E | |
| SCHEMBL9165551 | 0.79 | ALDH1A1 (0.48) | HSD17B10KMT2AMEN1 | |
| SCHEMBL15218450 | 0.79 | EP300 (0.64) | EP300KAT2BKAT8KEAP1KDM4E | |
| SCHEMBL11509065 | 0.77 | KEAP1 (0.77) | EP300KAT2BKAT8KEAP1KDM4E | |
| SCHEMBL29469801 | 0.77 | KMT2A (0.57) | KDM4EHPGDKMT2AMEN1CCR8 | |
| SCHEMBL1855816 | 0.77 | KMT2A (0.57) | KDM4EHPGDKMT2AMEN1CCR8 | |
| SCHEMBL13483435 | 0.77 | EP300 (0.66) | EP300KAT2BKAT8KEAP1KDM4E | |
| SCHEMBL8906416 | 0.76 | KEAP1 (0.48) | EP300KAT2BKAT8KEAP1KDM4E | |
| SCHEMBL15894583 | 0.75 | EP300 (1.00) | EP300KAT2BKAT8KEAP1KDM4E | |
| SCHEMBL30669737 | 0.75 | EP300 (1.00) | EP300KAT2BKAT8KEAP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1016653-B1 | Preparation of high-dye yield couplers and intermediates useful therein | EASTMAN KODAK CO (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6172260-B1 | Preparation of high dye-yield couplers and intermediates useful therein | EASTMAN KODAK COMPANY | 2001-01-09 | — | — | US | disclosed |
| US-6132944-A | A FORMED CARBAMYLOXY GROUP OR A SULFONYLISOCYANATO GROUP LINKED A COUPLER AND A DYE; EXHIBIT A HIGHER REACTIVITY WITH OXIDIZED DEVELOPER | EASTMAN KODAK COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| EP-1016916-A1 | Photographic element containing high dye-yield couplers | EASTMAN KODAK COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-1016653-A1 | Preparation of high-dye yield couplers and intermediates useful therein | EASTMAN KODAK COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| CN-1258861-A | Photographic element containing high dye productivity colour former | EASTMAN KODAK CO (US) | 2000-07-05 | — | — | CN | disclosed |