Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.38 |
| ▸ | PGR | P06401 | 5/20 | 0.38 |
| ▸ | AR | P10275 | 5/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554539 | 0.76 | EP300 (0.60) | KEAP1EP300KAT2BKAT8KDM4E | |
| SCHEMBL6400356 | 0.76 | CA2 (0.33) | L3MBTL1HTT | |
| SCHEMBL11509065 | 0.75 | KEAP1 (0.77) | KEAP1EP300KAT2BKAT8KDM4E | |
| SCHEMBL29274244 | 0.70 | KEAP1 (0.80) | KEAP1EP300KAT2BKAT8KDM4E | |
| SCHEMBL30956225 | 0.70 | KEAP1 (0.80) | KEAP1EP300KAT2BKAT8KDM4E | |
| SCHEMBL10823254 | 0.68 | CASP6 (0.43) | KDM4EHPGDHSD17B10PARP14HTT | |
| SCHEMBL8907308 | 0.68 | HSD11B1 (0.36) | NFE2L2PGR | |
| SCHEMBL10833613 | 0.67 | EP300 (0.48) | KEAP1EP300KAT2BKAT8KDM4E | |
| SCHEMBL4583715 | 0.66 | EP300 (0.80) | KEAP1EP300KAT2BKAT8KDM4E | |
| SCHEMBL2124660 | 0.66 | KEAP1 (1.00) | KEAP1EP300KAT2BKAT8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612173-A | INDOPHENOL DYE | EASTMAN KODAK COMPANY (US) | 1997-03-18 | — | — | US | disclosed |
| EP-0574090-A1 | One equivalent couplers and low pKa release dyes | EASTMAN KODAK COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |