Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554629 | 1.00 | KDM4E (0.50) | KDM4ETDP1PTGER1SMN1; SMN2LMNA | |
| SCHEMBL6555530 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAADRB2DRD2DRD1 | |
| SCHEMBL7782483 | 0.86 | KDM4E (0.47) | KDM4ETDP1PTGER1SMN1; SMN2LMNA | |
| SCHEMBL7605247 | 0.82 | MTNR1A (0.56) | SMN1; SMN2LMNATSHRMTNR1AMTNR1B | |
| SCHEMBL6555077 | 0.82 | ALDH1A1 (0.46) | SMN1; SMN2LMNATSHRMAPTMEN1 | |
| SCHEMBL6555072 | 0.82 | ALDH1A1 (0.46) | SMN1; SMN2LMNATSHRMAPTMEN1 | |
| SCHEMBL6556087 | 0.81 | ADRB2 (0.48) | PTGER1SMN1; SMN2LMNAADRB2MAPT | |
| SCHEMBL7155558 | 0.81 | ADRB2 (0.48) | PTGER1SMN1; SMN2LMNAADRB2MAPT | |
| SCHEMBL6554951 | 0.81 | ALDH1A1 (0.48) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL6556788 | 0.81 | ALDH1A1 (0.60) | PTGER1SMN1; SMN2LMNACTSDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135369-B1 | ALPHA-SULFIN- AND ALPHA-SULFONAMINO ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-25 | — | — | EP | disclosed |
| US-20020099241-A1 | For use in protecting plants against infestation by phytopathogenic microorganisms | SYNGENTA PARTICIPATIONS AG (CH) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099241-A1 | For use in protecting plants against infestation by phytopathogenic microorganisms | CBR1, CBR3, MSR1 | KDM4E 3338/4885TDP1 4292/4885PTGER1 2038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.