Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554629 | 0.86 | KDM4E (0.50) | KDM4ETDP1PTGER1LMNASMN1; SMN2 | |
| SCHEMBL6554633 | 0.86 | KDM4E (0.50) | KDM4ETDP1PTGER1LMNASMN1; SMN2 | |
| SCHEMBL7605247 | 0.76 | MTNR1A (0.56) | LMNASMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL6553382 | 0.74 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6553375 | 0.74 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6555077 | 0.73 | ALDH1A1 (0.46) | LMNASMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL6554892 | 0.73 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL7612458 | 0.73 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL6555072 | 0.73 | ALDH1A1 (0.46) | LMNASMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL6554873 | 0.73 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135369-A2 | ALPHA-SULFIN- AND ALPHA-SULFONAMINO ACID AMIDES | Syngenta Participations AG (CH) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000032569-A2 | ALPHA-SULFIN- AND ALPHA-SULFONAMINO ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-06-08 | — | — | WO | disclosed |