Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556215 | 0.80 | ALOX5 (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15672376 | 0.79 | PTGS2 (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7916764 | 0.75 | HTR2A (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29939055 | 0.74 | PTGS1 (0.57) | — | |
| SCHEMBL4603040 | 0.74 | PTGS1 (0.57) | — | |
| SCHEMBL14226993 | 0.73 | THRB (0.44) | KMT2AALOX5PTGS2MEN1MAPT | |
| SCHEMBL27419937 | 0.73 | ATM (0.51) | KMT2AMAPT | |
| SCHEMBL3037296 | 0.72 | TAAR1 (0.56) | ALOX5 | |
| SCHEMBL6554919 | 0.70 | ALOX5 (0.47) | KMT2AALOX5TNKS2 | |
| SCHEMBL14226990 | 0.70 | PTGS2 (0.46) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214327-B1 | BLOCKED PHENYLALKYL SILANES | CROMPTON CORP (US) | 2004-02-25 | — | — | EP | claimed |
| US-6559329-B2 | Deblocking of a trialkoxysilane compound acontaining carbonate or acetooxy group is done by hydrolysis or alcoholyis | CROMPTON CORPORATION | 2003-05-06 | — | — | US | claimed |
| US-6413646-B1 | Blocked phenolic silanes | CROMPTON CORPORATION | 2002-07-02 | — | — | US | claimed |
| US-20020051890-A1 | Blocked phenolic silanes | WITCO CORPORATION | 2002-05-02 | — | — | US | claimed |
| EP-1214327-B1 | BLOCKED PHENYLALKYL SILANES | CROMPTON CORP (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6559329-B2 | Deblocking of a trialkoxysilane compound acontaining carbonate or acetooxy group is done by hydrolysis or alcoholyis | CROMPTON CORPORATION | 2003-05-06 | — | — | US | disclosed |
| US-6413646-B1 | Blocked phenolic silanes | CROMPTON CORPORATION | 2002-07-02 | — | — | US | disclosed |
| US-20020051890-A1 | Blocked phenolic silanes | WITCO CORPORATION | 2002-05-02 | — | — | US | disclosed |