Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556215 | 0.89 | ALOX5 (0.43) | ALOX5TNKS2MTNR1AMTNR1BKMT2A | |
| SCHEMBL4603040 | 0.74 | PTGS1 (0.57) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL29939055 | 0.74 | PTGS1 (0.57) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL25916981 | 0.72 | MTNR1A (0.40) | MTNR1AMTNR1BKMT2AALDH1A1 | |
| SCHEMBL6554957 | 0.70 | TUBB4A (0.42) | ALOX5TNKS2KMT2A | |
| SCHEMBL6555269 | 0.69 | SMN1; SMN2 (0.49) | KMT2A | |
| SCHEMBL1639310 | 0.67 | CALM1 (0.45) | ALOX5ALDH1A1 | |
| SCHEMBL15733506 | 0.67 | IDO1 (0.36) | TNKS2 | |
| SCHEMBL17354076 | 0.67 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL27852474 | 0.67 | AKT1 (0.46) | ALOX5KMT2ABACE1AKT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214327-B1 | BLOCKED PHENYLALKYL SILANES | CROMPTON CORP (US) | 2004-02-25 | — | — | EP | claimed |
| US-6559329-B2 | Deblocking of a trialkoxysilane compound acontaining carbonate or acetooxy group is done by hydrolysis or alcoholyis | CROMPTON CORPORATION | 2003-05-06 | — | — | US | claimed |
| US-6413646-B1 | Blocked phenolic silanes | CROMPTON CORPORATION | 2002-07-02 | — | — | US | claimed |
| EP-1214327-A1 | BLOCKED PHENOLIC SILANES | Crompton Corporation (US) | 2002-06-19 | — | — | EP | claimed |
| US-20020051890-A1 | Blocked phenolic silanes | WITCO CORPORATION | 2002-05-02 | — | — | US | claimed |
| WO-2001009145-A1 | BLOCKED PHENOLIC SILANES | CROMPTON CORPORATION (US) | 2001-02-08 | — | — | WO | claimed |
| EP-1214327-B1 | BLOCKED PHENYLALKYL SILANES | CROMPTON CORP (US) | 2004-02-25 | — | — | EP | disclosed |
| US-6559329-B2 | Deblocking of a trialkoxysilane compound acontaining carbonate or acetooxy group is done by hydrolysis or alcoholyis | CROMPTON CORPORATION | 2003-05-06 | — | — | US | disclosed |
| US-6413646-B1 | Blocked phenolic silanes | CROMPTON CORPORATION | 2002-07-02 | — | — | US | disclosed |
| US-20020051890-A1 | Blocked phenolic silanes | WITCO CORPORATION | 2002-05-02 | — | — | US | disclosed |