Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235001 | 0.84 | PIM1 (0.35) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL1199490 | 0.78 | ALDH1A1 (0.39) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL7654635 | 0.77 | PIM1 (0.39) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL9516130 | 0.76 | PIM1 (0.38) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL6555080 | 0.74 | PIM1 (0.35) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL1089057 | 0.73 | PIM1 (0.37) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL4149607 | 0.73 | PIM1 (0.37) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL20864185 | 0.72 | FAAH (0.43) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL16060936 | 0.72 | PIM1 (0.36) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL9767895 | 0.72 | MAPK1 (0.37) | PIM1MARK3MAP4K2CAMK2BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708179-B1 | Glucagon-like insulinotropic peptide analogs, compositions, and methods of use | LILLY CO ELI (US) | 2004-12-22 | — | — | EP | disclosed |
| EP-1227151-A1 | Glucagon-like insulinotropic peptide analogs, compositions, and methods of use | ELI LILLY AND COMPANY (US) | 2002-07-31 | — | — | EP | disclosed |
| US-5512549-A | ANTIDIABETIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0708179-A2 | Glucagon-like insulinotropic peptide analogs, compositions, and methods of use | ELI LILLY AND COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |