Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516130 | 0.81 | PIM1 (0.38) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL1199490 | 0.79 | ALDH1A1 (0.39) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL4149607 | 0.78 | PIM1 (0.37) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL1089057 | 0.78 | PIM1 (0.37) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL6555359 | 0.77 | PIM1 (0.38) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL16060936 | 0.77 | PIM1 (0.36) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL20864185 | 0.77 | FAAH (0.43) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL6555080 | 0.76 | PIM1 (0.35) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL8312657 | 0.76 | GPR119 (0.36) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL27843880 | 0.74 | TSHR (0.32) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562896-B2 | 6-5 fused rings as C5a inhibitors | CHEMOCENTRYX, INC. (US) | 2020-02-18 | — | — | US | disclosed |
| US-6410744-B1 | REACTING AN IMIDAZOLE COMPOUND WITH PHOSGENE IN A SOLVENT | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562896-B2 | 6-5 fused rings as C5a inhibitors | C5AR1, C5AR2, C3AR1 | PIM1 4314/4885MARK3 4654/4885MAP4K2 1824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.