Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1089057 | 0.82 | PIM1 (0.37) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL1199490 | 0.74 | ALDH1A1 (0.39) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL7654635 | 0.73 | PIM1 (0.39) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL9516130 | 0.72 | PIM1 (0.38) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL6555359 | 0.72 | PIM1 (0.38) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL6570159 | 0.72 | TBXAS1 (0.43) | MAPK1KMT2ATBXAS1KDM4EBLM | |
| SCHEMBL5591568 | 0.72 | TBXAS1 (0.43) | MAPK1KMT2ATBXAS1KDM4EBLM | |
| SCHEMBL6555080 | 0.71 | PIM1 (0.35) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL4149607 | 0.70 | PIM1 (0.37) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL16060936 | 0.69 | PIM1 (0.36) | PIM1MARK3MAP4K2CAMK2BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006548-A | Hyaluronidase inhibitors, antiallergens, immunomodulators | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0153850-B1 | ACRYLAMIDOBENZOIC ACID DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0153850-A1 | Acrylamidobenzoic acid derivatives and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1985-09-04 | — | — | EP | disclosed |