SCHEMBL6555604

SCHEMBL6555604

C=CCS(=O)(=O)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
PRSS1 P07477 2/20 0.48
PRSS2 P07478 2/20 0.48
PRSS3 P35030 2/20 0.48
FAAH O00519 1/20 0.48
ELANE P08246 1/20 0.48
PRTN3 P24158 1/20 0.48
CA5A P35218 1/20 0.48
CA9 Q16790 1/20 0.48
MMP1 P03956 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
MMP13 P45452 1/20 0.44
KMT2A Q03164 3/20 0.42
LMNA P02545 1/20 0.41
HSP90AA1 P07900 1/20 0.40
F2 P00734 1/20 0.40
HPGD P15428 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10082509 0.81 CA1 (0.50) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL5412467 0.80 CA2 (0.55) CA1CA2CA9MMP1MMP8
SCHEMBL11759715 0.80 CA1 (0.45) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL24188595 0.80 SMN1; SMN2 (0.41) CA1CA2CA9KMT2ALMNA
SCHEMBL88641 0.79 CA2 (0.64) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL790380 0.78 CA1 (0.41) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL10728660 0.78 CA1 (0.37) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL10728655 0.78 CA1 (0.37) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL24188497 0.77 TGM2 (0.40)
SCHEMBL11332772 0.77 TDP1 (0.46) CA1CA2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220009882-A1 ORGANOSULFUR COMPOUNDS MARIPOSA THERAPEUTICS LTD. (GB) 2022-01-13 US disclosed
CN-104379560-A Benzamide derivative CHUGAI PHARMACEUTICAL CO LTD 2015-02-25 CN disclosed
CN-104379568-A Quinazolinedione derivative CHUGAI PHARMACEUTICAL CO LTD 2015-02-25 CN disclosed
EP-1124893-B1 POLYISOCYANATE POLYADDITION PRODUCTS BASF AG (DE) 2004-12-22 EP disclosed
CN-1543452-A 1, 4-disubstituted benzene insecticides FMC 2004-11-03 CN disclosed
US-20040209969-A1 Polyisocyanate polyaddition products ARLT ANDREAS 2004-10-21 US disclosed
US-6794421-B2 comprising hydrophobic compounds plus at least one further compound and/or derivative thereof reactive toward primary amines, compound being selected from cyclic sulfonic esters and sulfones and mixtures thereof BASF AKTIENGESELLSCHAFT (DE) 2004-09-21 US disclosed
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
US-20030130366-A1 Polyisocyanate polyaddition products ARLT ANDREAS (DE) 2003-07-10 US disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed
EP-0380578-B1 A PROCESS FOR THE PREPARATION OF 1,4-DISUBSTITUTED 2-BUTENES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1993-03-17 EP disclosed
US-5189199-A Process for the preparation of 1,4-disubstituted 2-butenes EASTMAN KODAK COMPANY (US) 1993-02-23 US disclosed
EP-0270271-B1 BONDING OF HALOGENATED ORGANIC COMPOUNDS KENRICH PETROCHEMICALS, INC. (US) 1992-08-19 EP disclosed
EP-0380578-A1 A PROCESS FOR THE PREPARATION OF 1,4-DISUBSTITUTED 2-BUTENES. EASTMAN KODAK CO (US) 1990-08-08 EP disclosed
WO-1989002883-A1 A PROCESS FOR THE PREPARATION OF 1,4-DISUBSTITUTED 2-BUTENES EASTMAN KODAK COMPANY (US) 1989-04-06 WO disclosed
US-4816522-A ADHESIVES, ZIRCONATE COMPOUNDS KENRICH PETROCHEMICALS (US) 1989-03-28 US disclosed
US-4753848-A PRETREATMENT WITH ORGANOZIRCONATE KENRICH PETROCHEMICALS, INC. (US) 1988-06-28 US disclosed
EP-0270271-A2 Bonding of halogenated organic compounds KENRICH PETROCHEMICALS, INC. (US) 1988-06-08 EP disclosed
US-4525555-A TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS NIPPON OIL COMPANY, LIMITED (JP) 1985-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220009882-A1 ORGANOSULFUR COMPOUNDS F3, F2, TST CA1 4848/4885CA2 4604/4885PRSS1 76/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.