Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPN | P05981 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6555941 | 0.85 | PGR (0.49) | PGRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9810965 | 0.81 | PGR (0.46) | PGRMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL9810975 | 0.79 | MAOA (0.46) | PGRMAPTCYP3A4TSHRALDH1A1 | |
| SCHEMBL24726895 | 0.78 | HSP90AA1 (0.44) | PGRL3MBTL1NPC1RAB9ACA1 | |
| SCHEMBL6701148 | 0.78 | MAPT (0.58) | PGRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL24726975 | 0.78 | PGR (0.44) | PGRMAPTCYP3A4TSHRALDH1A1 | |
| SCHEMBL6558028 | 0.76 | PGR (0.39) | PGRSRD5A1HTR2BDRD2DRD3 | |
| SCHEMBL6555913 | 0.75 | SMN1; SMN2 (0.53) | PGRMAPTCYP3A4TSHRALDH1A1 | |
| SCHEMBL9811023 | 0.72 | TLR9 (0.54) | PGRMAPTTSHRALDH1A1MEN1 | |
| SCHEMBL6558006 | 0.72 | PGR (0.42) | PGRNOTUMSRD5A1NOS3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223209-B1 | Fluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INT LTD (CH) | 2004-03-03 | — | — | EP | disclosed |
| EP-1223209-A1 | Fluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INTERNATIONAL LTD. (CH) | 2002-07-17 | — | — | EP | disclosed |