Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810965 | 0.89 | PGR (0.46) | PGRPARP1MAPK1AKR1A1AKR1B1 | |
| SCHEMBL6555960 | 0.85 | PGR (0.51) | PGRMAPK1NOS3KDM4ENPC1 | |
| SCHEMBL9810975 | 0.80 | MAOA (0.46) | PGRMAPK1NOS3KDM4ENPC1 | |
| SCHEMBL4896474 | 0.77 | PARP1 (0.45) | PGRPARP1MAPK1HTR2AHTR2C | |
| SCHEMBL6558006 | 0.76 | PGR (0.42) | PGRPARP1AKR1A1AKR1B1NOS3 | |
| SCHEMBL6557452 | 0.76 | ALDH1A1 (0.53) | PGRPARP1MAPK1HTR2AHTR2C | |
| SCHEMBL24726975 | 0.75 | PGR (0.44) | PGRHTR2AALDH1A1MAPTCA1 | |
| SCHEMBL6701148 | 0.75 | MAPT (0.58) | PGRPARP1NOS3KDM4ENPC1 | |
| SCHEMBL24726895 | 0.75 | HSP90AA1 (0.44) | PGRHTR2AHTR2CNPC1RAB9A | |
| SCHEMBL29851576 | 0.72 | ALDH1A1 (0.59) | PGRPARP1MAPK1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223209-B1 | Fluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INT LTD (CH) | 2004-03-03 | — | — | EP | disclosed |
| EP-1223209-A1 | Fluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INTERNATIONAL LTD. (CH) | 2002-07-17 | — | — | EP | disclosed |