Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558006 | 0.79 | PGR (0.42) | PGRDRD2DRD3SRD5A1HTR7 | |
| SCHEMBL6555945 | 0.78 | PNMT (0.41) | DRD2HTR7HTR2B | |
| SCHEMBL4011638 | 0.77 | DRD2 (0.34) | PGRDRD2DRD3SRD5A1 | |
| SCHEMBL6555960 | 0.76 | PGR (0.51) | PGRDRD2DRD3SRD5A1HTR2B | |
| SCHEMBL30488646 | 0.71 | PGR (0.36) | PGRDRD2DRD3SRD5A1HTR7 | |
| SCHEMBL9810975 | 0.71 | MAOA (0.46) | PGRDRD2DRD3HTR2B | |
| SCHEMBL6555941 | 0.69 | PGR (0.49) | PGR | |
| SCHEMBL9810965 | 0.69 | PGR (0.46) | PGR | |
| SCHEMBL22539769 | 0.69 | PGR (0.43) | PGR | |
| SCHEMBL1912510 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223209-B1 | Fluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INT LTD (CH) | 2004-03-03 | — | — | EP | disclosed |
| EP-1223209-A1 | Fluorinated fluorenes and use thereof in liquid crystal mixtures | CLARIANT INTERNATIONAL LTD. (CH) | 2002-07-17 | — | — | EP | disclosed |